Table 2 Demographic comparison between healthy controls and repaired tetralogy of Fallot (rTOF)
|  | Healthy Control (n = 63) | rTOF (n = 63) | P |
|---|---|---|---|
Demographics | |||
 Age at CMR, yrs | 30 [22, 42] | 29 [21, 41] | 0.695 |
 Age at primary repair, yrs* | – | 3 [1.25, 7.25] | – |
 Time after primary repair, yrs* | – | 25 [20, 33] | – |
 Gender, M/F, n | 29/34 | 29/34 | 1.000 |
 Height, cm | 161 ± 14 | 159 ± 13 | 0.551 |
 Weight, kg | 58 ± 18 | 57 ± 18 | 0.966 |
 Body surface area, m2 | 1.59 ± 0.31 | 1.58 ± 0.30 | 0.741 |
 Body mass index, kg/m2 | 21.8 ± 4.5 | 22.1 ± 5.5 | 0.729 |
 Heart rate, bpm | 75 ± 14 | 77 ± 12 | 0.483 |
Tricuspid regurgitation | Â | Â | Â |
 No | 63 (100%) | 28 (44%) | – |
 Mild | – | 28 (44%) | – |
 Moderate to severe | – | 7 (12%) | – |
Numbers with re-intervention | – | 17 (27%) | – |
Pulmonary valve replacement | – | 1 (2%) | – |
Types of repair†|  |  | – |
 Transannular patch | – | 45 (71%) | – |
 Valve-sparing | – | Unknown | – |
 Conduit | – | Unknown | – |
Right ventricular outflow tract dyskinesia | – | 43 (68%) | – |
Restrictive physiology | – | 43 (68%) | – |
LV function | |||
 LV mass index, g/m2 | 41 ± 8 | 41 ± 11 | 0.998 |
 LV end-diastolic volume index, ml/m2 | 79 ± 13 | 78 ± 16 | 0.850 |
 LV end-systolic volume index, ml/m2 | 33 ± 7 | 34 ± 11 | 0.496 |
 LV stroke volume index, ml/m2 | 46 ± 8 | 44 ± 9 | 0.306 |
 LV ejection fraction, % | 58 ± 5 | 57 ± 7 | 0.242 |
RV function | |||
 RV end-diastolic volume index, ml/m2 | 77 ± 14 | 133 ± 31 |  < 0.001 |
 RV end-systolic volume index, ml/m2 | 36 ± 9 | 73 ± 23 |  < 0.001 |
 RV stroke volume index, ml/m2 | 41 ± 7 | 60 ± 15 |  < 0.001 |
 RV ejection fraction, % | 54 ± 6 | 46 ± 8 |  < 0.001 |
 RVEDV/LVEDV ratio | 0.99 ± 0.12 | 1.75 ± 0.49 |  < 0.001 |
Pulmonary regurgitant volume, ml | – | 44 ± 25 | – |
Pulmonary regurgitant fraction, % | – | 43.5 ± 16.6 | – |
Pulmonary valve annulus diameter, cm | 2.2 ± 0.3 | 2.7 ± 0.6 |  < 0.001 |
Pulse wave velocity, m/s | 1.9 ± 0.8 | 3.3 ± 1.9 |  < 0.01 |