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Table 2 Clinical and treatment characteristics

From: Myocardial involvement in children with post-COVID multisystem inflammatory syndrome: a cardiovascular magnetic resonance based multicenter international study—the CARDOVID registry

  Total
n = 111
Myocarditis
(Group 1)
(n = 20)
No myocarditis (Group 2)
(n = 91)
p-value
Fever 111/11 (100) 20/20 (100) 91/91 (100) NA
Adenopathy 27/91 (30) 5/15 (33) 22/76 (29) 0.762
Respiratory symptoms 35/97 (36) 8/16 (50) 27/81 (33) 0.257
Gastrointestinal symptoms 89/107 (83) 15/18 (83) 74/89 (83) 0.999
Cutaneous symptoms 70/102 (69) 12/16 (75) 58/86 (67) 0.770
Syncope 1/108 (1) 0/17 1/91 (1) 0.999
Palpitation 13/96 (14) 3/15 (20) 10/81 (12) 0.422
Arrhythmias 7/104 (7) 3/17 (18) 4/87 (5) 0.084
Chest pain 12/94 (13) 4/16 (25) 8/78 (10) 0.118
Dyspnea 34/100 (34) 8/16 (50) 26/84 (31) 0.159
NYHA class I 68/93 (73) 8/15 (53) 60/78 (77) 0.011*
 class II 2/93 (2) 0/15 2/78 (3)  
 class III 8/93 (9) 0/15 8/78 (10)  
 class IV 15/93 (16) 7/15 (47) 8/78 (10)  
Hospitalization ICU 87/111 (78) 15/20 (75) 72/91 (79) 0.765
Arrhythmias during hospitalization 7/86 (8) 3/14 (21) 4/72 (6) 0.082
Respiratory failure 45/105 (43) 7/16 (44) 38/89 (43) 0.999
Circulation failure 69/107 (64) 9/18 (50) 60/89 (67) 0.183
Renal failure 34/104 (33) 2/17 (12) 32/87 (37) 0.051
Treatment     
Inotropic support 71/100 (71) 11/16 (69) 60/84 (71) 0.999
Mechanical support 9/103 (9) 4/17 (24) 5/86 (6) 0.039
Ventilation support 40/98 (41) 6/14 (43) 34/84 (40) 0.999
Immunosuppressive therapy during hospitalization 66/90 (73) 12/16 (75) 54/74 (73) 0.999
Corticosteroids 91/109 (83) 17/20 (85) 74/89 (83) 0.999
IVIG 98/109 (90) 17/19 (89) 81/90 (90) 0.999
Antiaggregant therapy 84/106 (79) 14/18 (78) 70/88 (80) 0.999
Anticoagulant therapy 66/105 (63) 12/19 (63) 53/86 (63) 0.999
Death 0 0 0 NA
  1. Bold p values were significative
  2. Values are presented as absolute numbers (%). Def  definition, Hosp  hospitalization, ICU intensive care unit, IVIG intravenous immunoglobulin, NYHA New York Heart Association. The denominator for each field is reflective of the total number of available data entry points. *NYHA 1 vs NYHA 4 p = 0.005