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Table 1 Characteristics and Imaging Data of the Included Studies

From: Cardiovascular magnetic resonance native T1 mapping in Anderson-Fabry disease: a systematic review and meta-analysis

Reference Study design Study type Field strength Sequence ROI sampling Quality score LVH (%) LVEF (%) Native T1 (ms)
AFD patients Control subjects AFD patients Control subjects AFD patients Control subjects
[15] Prospective Single center 1.5T MOLLI Mean basal-mid SAx 2, 1, 2  −  0 66 ± 6 66 ± 7 930 ± 54 1000 ± 34
[16] Retrospective Single center 1.5T MOLLI Mean 3 SAx 4, 1, 2 53 0 59 ± 11 63 ± 5 891 ± 49 966 ± 27
[18] Prospective Multi-center 1.5T MOLLI Mean 3 Sax & LAx 3, 1, 2 0 0 58 ± 9 67 ± 4 961 ± 53 1029 ± 38
[24] Prospective Single center 1.5T MOLLI Mean 16 AHA 3, 1, 2 24 0 66 ± 12 66 ± 8 903 ± 14*
888 ± 70**
1001 ± 22
[20] Prospective Single center 1.5T ShMOLLI Mean mid-septum
SAx & LAx
2, 1, 2 0 0 72 ± 6  −  906 ± 68 970 ± 21
[22] Retrospective Single center 1.5T ShMOLLI Mid-septum SAx 4, 1, 2  −  0 60 ± 15 66 ± 9 863 ± 23 938 ± 21
[25] Prospective Single center 1.5T ShMOLLI Mean basal-mid-septum SAx 3, 1, 2 60 0 74 ± 6*
78 ± 7**
75 ± 7 904 ± 46*
853 ± 50**
968 ± 32
[26] Prospective Single center 1.5T ShMOLLI Mean basal-mid-septum SAx 3, 1, 2 55 0  −   −  882 ± 47 968 ± 32
[23] Retrospective Single center 1.5T SASHA Mid-septum SAx 3, 1, 2  −  0 67 ± 7 62 ± 5 1053 ± 41 1180 ± 60
[27] Prospective Single center 1.5T SASHA Mean basal-mid SAx 3, 1, 2 52 0 67 ± 5 64 ± 4 1070 ± 50 1177 ± 27
[14] Prospective Single center 3T MOLLI Mean 16 AHA 4, 1, 2 14 0 67 ± 12 67 ± 2 1112 ± 49 1232 ± 12
[17] Prospective Single center 3T MOLLI Mean 16 AHA 4, 1, 2 19 0 60 ± 5 62 ± 3 1164 ± 34 1235 ± 25
[19] Prospective Single center 3T MOLLI Mid-septum SAx 4, 1, 2 21 0 59 ± 5 60 ± 4 1170 ± 37 1238 ± 18
[21] Prospective Single center 3T MOLLI Mean 3 SAx 4, 1, 2 0 0 69 ± 7 66 ± 3 1236 ± 49 1334 ± 27
  1. Values are expressed as mean ± standard deviation or as percentage of subjects. ROI region of interest, SAx short axis, LAx long axis, AHA American Heart Association, MOLLI modified look-locker inversion recovery, ShMOLLI shortened MOLLI, SASHA saturation-recovery single-shot acquisition, LVH left ventricular hypertrophy, LVEF left ventricular ejection fraction. *Patients without and **patients with left ventricular hypertrophy