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Table 1 Advantages and disadvantages of echocardiography and cardiovascular magnetic resonance in assessment of valvular heart disease

From: Rationale and clinical applications of 4D flow cardiovascular magnetic resonance in assessment of valvular heart disease: a comprehensive review

Modality

Advantages

Disadvantages

Transthoracic echocardiography (TTE)

Widely available [6]

Inexpensive [5]

Safe [4]

Limited accuracy in patients with large body habitus and chronic obstructive pulmonary disease [7]

Limited accuracy in the presence of eccentric/multiple regurgitant jets [9]

Suboptimal assessment of right heart [8]

Transoesophageal echocardiography

Not limited by body habitus [44]

Superior image quality when TTE is suboptimal [1]

Visualisation of structures not assessed by TTE e.g. left atrial appendage [1]

Moderately invasive. Risk of bleeding and oesophageal perforation [44]

Requires presence of trained medical personnel [44]

Potential complications of sedation [44]

Reduced utility during pandemic due to high aerosol production [45]

Standard CMR (LV/RV cine stack, PCMR and LGE)

Reference-standard left and right ventricular size and function assessment [14, 15]

Accurate indirect quantification of atrio-ventricular valve regurgitation, even in the presence of eccentric and multiple jets [39]

Tissue phenotyping/quantification of fibrosis [46]

Inaccurate direct quantification of atrio-ventricular valvular regurgitation [13]

Potential for error in stroke volume calculation [6]

Limited by claustrophobia/arrhythmia [6, 47]

4D flow CMR

Regurgitant jet visualisation [22]

Direct regurgitant jet quantification [9]

No geometric assumptions [22]

Simultaneous analysis of flow across all four valves [25]

Accurate peak velocity assessment vs. PCMR [31]

May be advantageous in combined valve lesions [22]

Measurement of fluid biomechanics [29]

Simple acquisition [29]

Free-breathing [23]

Plane reformatting is possible [25]

Time-consuming post-processing [29]

Limited temporal and spatial resolution [29]

Limited software availability [16]

  1. CMR = cardiovascular magnetic resonance; LGE = late gadolinium enhancement; LV = left ventricle; PCMR = phase contrast magnetic resonance; RV = right ventricle; TTE = transthoracic echocardiography