Ferumoxytol (n = 21) | Gadolinium (n = 23) | p value | |
---|---|---|---|
Age (years) | 2.1 ± 1.6 | 2.3 ± 1.9 | 0.841 |
Male sex | 9 (43%) | 13 (57%) | 0.377 |
Height (cm) | 81.8 ± 19.1 | 84.0 ± 18.3 | 0.706 |
Weight (kg) | 11.5 ± 5.1 | 12.2 ± 4.8 | 0.599 |
BSA (m2) | 0.5 ± 0.2 | 0.52 ± 0.2 | 0.667 |
Great vessel diameter (mm) | 16.3 ± 5.0 | 15.7 ± 5.9 | 0.575 |
Branch pulmonary arteries (mm) | 9.0 ± 3.1 | 9.5 ± 2.7 | 0.267 |
Pulmonary vein diameter (mm) | 7.2 ± 1.6 | 7.6 ± 2.0 | 0.889 |
Caval diameter (mm) | 12.7 ± 3.9 | 10.7 ± 3.8 | 0.115 |
Diagnoses | |||
Single ventricle patients | 5 (24%) | 5 (22%) | 0.874 |
Conotruncal anomalies | 7 (33%) | 13 (56%) | 0.129 |
Anomalous systemic or pulmonary venous drainage | 6 (29%) | 3 (13%) | 0.211 |
Septal defects and AV valve anomalies | 3 (14%) | 2 (9%) | 0.570 |
Study indication | |||
Eval anatomy, function, chamber size, Qp:Qs | 10 (48%) | 10 (43%) | 0.789 |
Eval outflow tract obstruction/regurgitation | 1 (4%) | 1 (4%) | 0.949 |
Eval branch pa stenosis/flow differential | 5 (24%) | 8 (35%) | 0.437 |
Pre-Glenn/Pre-Fontan | 5 (24%) | 4 (18%) | 0.608 |
Use of anesthesia | |||
Moderate sedation or feed and bundle | 7 (33%) | 12 (52%) | 0.217 |
General anesthesia—ventilated | 14 (67%) | 11 (48%) | 0.217 |
Resolution 4D (mm) | |||
1.30 × 1.25 × 1.25 | 15 (71%) | 3 (13%) | < 0.001 |
1.80 × 1.75 × 1.75 | 6 (29%) | 20 (87%) | < 0.001 |