Table 3 Comparison of 31P-CMRS and CMR findings between patients with long COVID-19 syndrome and healthy subjects
Variable | Healthy subjects (n = 10) | Long COVID-19 syndrome (n = 19) | p-value |
|---|---|---|---|
PCr/ATP ratio | 2.1 ± 0.5 | 2.2 ± 0.4 | 0.49 |
LV end diastolic volume (ml) | 158 ± 39 | 152 ± 22 | 0.68 |
LV end diastolic volume index (ml/m2) | 87 ± 20 | 81 ± 10 | 0.43 |
LV end systolic volume (ml) | 57 ± 12 | 60 ± 12 | 0.50 |
LV end systolic volume index (ml/m2) | 31 ± 7 | 32 ± 6 | 0.83 |
LV stroke volume (ml) | 93 [79–121] | 87 [81–110] | 0.26 |
LV ejection fraction (%) | 64 ± 4 | 61 ± 4 | 0.07 |
RV end diastolic volume (ml) | 170 ± 46 | 156 ± 29 | 0.41 |
RV end diastolic volume index (ml/m2) | 93 ± 23 | 83 ± 13 | 0.24 |
RV end systolic volume (ml) | 76 ± 25 | 67 ± 18 | 0.34 |
RV end systolic volume index (ml/m2) | 42 ± 12 | 36 ± 9 | 0.20 |
RV stroke volume (ml) | 93 ± 29 | 89 ± 17 | 0.64 |
RV ejection fraction (%) | 55 ± 8 | 57 ± 6 | 0.49 |
Peak circumferential strain (%) | − 21.0 ± 2.1 | − 20.7 ± 3.3 | 0.77 |
Global longitudinal strain (%) | − 13.3 ± 2.3 | − 11.9 ± 3.7 | 0.21 |
Peak diastolic circumferential strain rate (1/s) | 1.3 ± 0.2 | 1.3 ± 0.3 | 0.80 |
Peak diastolic longitudinal strain rate (1/s) | 1.0 ± 0.2 | 1.0 ± 0.4 | 0.98 |
Mean T1 (ms) | 1206 ± 64 | 1158 ± 114 | 0.15 |
Extra-cellular volume (%) | 25 ± 2 | 22 ± 5 | 0.03 |
T2 (ms) | 39 ± 2 | 40 ± 3 | 0.46 |
MBF rest (ml/g/min) | 0.7 ± 0.1 | 0.8 ± 0.3 | 0.20 |
MBF stress (ml/g/min) | 2.0 ± 0.5 | 2.1 ± 0.5 | 0.74 |
MPR | 3.1 ± 0.9 | 3.0 ± 0.8 | 0.89 |