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Table 5 Subgroup analysis of virally supressed individuals (< 200 copies/ml after the initiation on ART)

From: Evolution of myocardial oedema and fibrosis in HIV infected persons after the initiation of antiretroviral therapy: a prospective cardiovascular magnetic resonance study

Parameter

Virally supressed group

Virally supressed group

p value

n = 58

n = 58

(Naïve)

(ART)

CD4 count (cells/μl)

292 (152 to 432)

378 (274 to 633)

< 0.001

CD8 count (cells/μl)

789 (575 to 1044)

608 (456 to 821)

< 0.001

HIV viral load (copies/ml)

85,320 (11,604 to 298,008)

20* (20* to 22)

< 0.001

HIV viral load (log copies/ml)

4.9 (4.1 to 5.5)

1.3* (1.3* to 1.3*)

< 0.001

Presence of pericardial effusion

39 (67%)

35 (60%)

0.6

Global T2 SIR

1.5 ± 0.2

1.5 ± 0.2

0.5

Global native T1 mapping (ms)

1030 ± 48

1009 ± 31

< 0.001

Global native T2 mapping (ms)

48 ± 3

48 ± 2

0.2

Global ECV (%)

26 ± 4

24 ± 3

0.006

EGE

4.1 ± 2.8

3.7 ± 2.3

0.4

LGE present

28 (48%)

31 (53%)

0.5

  1. Bold values indicate p value of ≤ 0.05
  2. Continuous variables are mean ± standard deviation or median (interquartile range) unless otherwise specified
  3. LV left ventricle, RV right ventricle, SIR Signal intensity ratio, ECV Extracellular volume, LGE late gadolinium enhancement
  4. *20 copies/ml (log = 1.3) is the lower limit of measurement for our HIV-1 assay