Table 1 Baseline characteristics
Variables | All patients (n = 1046) | MACE (n = 73) | No MACE (n = 971) | p-value |
|---|---|---|---|---|
Age | 64 (53–73) | 71 Y | 63 (52–72) | < 0.001 |
Sex (male) | 784/1046 (75) | 49/73 (67.1) | 734/971 (75.6) | 0.14 |
Cardiovascular risk factors | ||||
Active smoking | 421/967 (40.2) | 21/66 (28.8) | 399/899 (41.1) | 0.047 |
Hypertension | 742/1044 (70.9) | 61/73 (83.6) | 679/969 (69.9) | 0.01 |
Hyperlipoproteinemia | 394/1041 (37.7) | 26/73 (35.6) | 367/966 (37.8) | 0.7 |
Diabetes | 246/1044 (23.7) | 25/73 (34.2) | 220/969 (22.7) | 0.03 |
Body mass index (kg/m2) | 27.5 (24.9–30.4) | 27.6 (25.4–31.1) | 27.4 (24.9–30.2) | 0.49 |
Previous myocardial infarction | 75/1044 (7.2) | 5/73 (6.8) | 69/969 (7.1) | 0.93 |
Previous PCI | 90/1045 (8.6) | 5/73 (6.8) | 84/970 (8.7) | 0.59 |
Previous CABG | 19/1046 (1.8) | 2/73 (2.7) | 17/970 (1.8) | 0.54 |
ST-segment elevation | 719/1046 (68.7) | 49/73 (67.1) | 670/971 (69) | 0.74 |
Systolic blood pressure (mmHg) | 133 (118–150) | 133 (100–150) | 133 (120–150) | 0.23 |
Diastolic blood pressure (mmHg) | 80 (70–89) | 78 (66–85) | 80 (70–89) | 0.08 |
Heart rate (bpm) | 76 (67–86) | 80 (70–95) | 76 (66–86) | 0.001 |
Time symptoms to balloon* (min) | 180 (109–317) | 194 (115–381) | 180 (108–310) | 0.22 |
Door-to-balloon time* (min) | 30 (22–42) | 28 (23–40) | 30 (22–42) | 0.45 |
Killip class on admission | < 0.001 | |||
1 | 925/1046 (88.4) | 48/73 (65.8) | 875/971 (90.1) | |
2 | 83/1046 (7.9) | 16/73 (21.9) | 67/971 (6.9) | |
3 | 22/1046 (2.1) | 5/73 (6.8) | 17/971 (1.8) | |
4 | 16/1046 (1.5) | 4/73 (5.5) | 12/971 (1.2) | |
Diseased vessels | 0.008 | |||
1 | 524/1046 (50.1) | 27/73 (37) | 496/971 (51.1) | |
2 | 315/1046 (30.1) | 22/73 (30.1) | 293/971 (30.2) | |
3 | 207/1046 (19.8) | 24/73 (32.9) | 182/971 (18.7) | |
Affected artery | 0.27 | |||
Left anterior descending | 430/1046 (41.1) | 38/73 (52.1) | 392/971 (40.4) | |
Left circumflex | 217/1046 (20.7) | 14/73 (19.2) | 201/971 (20.7) | |
Left main | 4/1046 (0.4) | 0/73 (0) | 4/971 (0.4) | |
Right | 388/1046 (37.1) | 20/73 (27.4) | 368/971 (37.9) | |
Bypass graft | 7/1046 (0.7) | 1/73 (1.4) | 6/971 (0.6) | |
TIMI flow grade before PCI | 0.62 | |||
0 | 524/1046 (50.1) | 41/73 56.2) | 482/971 (49.6) | |
1 | 112/1046 (10.7) | 5/73 (6.8) | 107/971 (11) | |
2 | 219/1046 (20.9) | 14/73 (19.2) | 204/971 (21) | |
3 | 191/1046 (18.3) | 13/73 (17.8) | 178/971 (18.3) | |
Stent implanted | 1022/1046 (97.7) | 71/73 (97.3) | 949/971 (97.7) | 0.62 |
TIMI flow grade after PCI | 0.11 | |||
0 | 20/1046 (1.9) | 1/73 (1.4) | 19/971 (2) | |
1 | 22/1046 (2.1) | 4/73 (5.5) | 18/971 (1.9) | |
2 | 78/1046 (7.5) | 8/73 (11) | 70/971 (7.2) | |
3 | 926/1046 (88.5) | 60/73 (82.2) | 864/971 (89) | |
Medication | ||||
Aspirin | 1044/1046 (99.8) | 73/73 (100) | 969/971 (99.8) | 0.7 |
Clopidogrel/Prasugrel/Ticagrelor | 741/1045 (70.8) | 73/73 (100) | 971/971 (100) | |
Betablocker | 1000/1046 (95.6) | 71/73 (97.3) | 927/970 (95.5) | 0.7 |
ACE-inhibitor/AT-1 antagonist | 961/1045 (91.9) | 69/73 (94.5) | 891/970 (91.8) | 0.42 |
Aldosterone antagonist | 137/1046 (13.1) | 24/73 (32.9) | 113/970 (11.6) | < 0.001 |
Statin | 1007/1045 (96.3) | 71/73 (97.3) | 934/970 (96.2) | 0.67 |
Time to CMR (days) | 3 (2–4) | 3 (2–4) | 3 (2–4) | 0.05 |