Fig. 6

Incremental value of global CFR. Incremental prognostic value of global CFR over coronary risk factors and ischemia is shown. Adding infarction to coronary risk factors (male, increased age, hypertension, dyslipidemia, diabetes, smoking, and family history of coronary artery disease) increased global chi-square values from 67 to 96 (p < 0.001), and then, by adding ischemia to coronary risk factors plus infarction, global chi-square values increased to 109 (p < 0.001). Further, a global chi-square value of 127 was achieved by adding global CFR on top of coronary risk factors + infarction + ischemia (p < 0.001)