Articles

2093 CMR reveals that cardiac-specific overexpression of the inducible form of nitric oxide synthase induces Left Ventricular Hypertrophy in wild-type mice after AAV-Mediated direct gene transfer

Authors: Konkal MR Prasad, Ronald J Beyers, Yaqin Xu, Frederick H Epstein and Brent A French

308 MR guidance and monitoring of intramyocardial delivery of VEGF Gene in coronary artery occlusion in canine model

Authors: Maythem Saeed, Alastair J Martin, Loi Do, Alexis Jacquier, Charles B Higgins and David Saloner

304 An non subjective method for myocardial T2* curve fitting in thalassemia

Authors: Taigang He, Gillian C Smith, Raad H Mohiaddin, Dudley J Pennell and David N Firmin

159 3D Submillimeter isotropic resolution superficial femoral artery wall MRI using SPACE at 3.0 T

Authors: Zhuoli Zhang, Zhaoyang Fan, YiuCho Chung, Peter Weale, Timothy Carroll, Ioannis Koktzoglou, Renate Jerecic, James Carr, Mary McGrae McDermott and Debiao Li

Meeting Highlights of the 11^th Annual Scientific Sessions of the Society for Cardiovascular Magnetic Resonance, Los Angeles, February 1–3, 2008

This paper features the most interesting presentations and discussions of the 2008 Annual Sessions of the Society for Cardiovascular Magnetic Resonance, which were held in Los Angeles from February 1 to 3, 2008.

Authors: Matthias G Friedrich, Warren J Manning, Thoralf Niendorf, Charles B Higgins, Albert de Roos and Stefan Neubauer

Routine clinical cardiovascular magnetic resonance in paediatric and adult congenital heart disease: patients, protocols, questions asked and contributions made

Cardiovascular Magnetic Resonance (CMR) of patients with congenital heart disease (CHD) has become routine clinical practice. However, existing CMR protocols focus predominantly on patients with ischemic heart...

Authors: Sohrab Fratz, John Hess, Annika Schuhbaeck, Christine Buchner, Eva Hendrich, Stefan Martinoff and Heiko Stern

Combined magnetic resonance coronary artery imaging, myocardial perfusion and late gadolinium enhancement in patients with suspected coronary artery disease

Cardiovascular Magnetic Resonance (CMR) imaging offers methods for the detection of ischemia and myocardial infarction as well as visualization of the coronary arteries (MRCA). However, a direct comparison of ...

Authors: Christoph Klein, Rolf Gebker, Thomas Kokocinski, Stephan Dreysse, Bernhard Schnackenburg, Eckart Fleck and Eike Nagel

Dobutamine stress cardiovascular magnetic resonance at 3 Tesla

The assessment of inducible wall motion abnormalities during high-dose dobutamine-stress cardiovascular magnetic resonance (DCMR) is well established for the identification of myocardial ischemia at 1.5 Tesla....

Authors: S Kelle, A Hamdan, B Schnackenburg, U Köhler, C Klein, E Nagel and E Fleck

Detection and quantification of angiogenesis in experimental valve disease with integrin-targeted nanoparticles and 19-fluorine MRI/MRS

Angiogenesis is a critical early feature of atherosclerotic plaque development and may also feature prominently in the pathogenesis of aortic valve stenosis. It has been shown that MRI can detect and quantify ...

Authors: Emily A Waters, Junjie Chen, John S Allen, Huiying Zhang, Gregory M Lanza and Samuel A Wickline

Improved survival of thalassaemia major in the UK and relation to T2* cardiovascular magnetic resonance

The UK Thalassaemia Register records births, deaths and selected clinical data of patients with thalassaemia who are resident in the UK. A study of survival and causes of death was undertaken which aimed to in...

Authors: Bernadette Modell, Maren Khan, Matthew Darlison, Mark A Westwood, David Ingram and Dudley J Pennell

Comparison of cardiovascular magnetic resonance of late gadolinium enhancement and diastolic wall thickness to predict recovery of left ventricular function after coronary artery bypass surgery

The objective was to compare the value of late gadolinium enhancement (LGE) and end-diastolic wall thickness (EDWT) assessed by cardiovascular magnetic resonance (CMR) in predicting recovery of left ventricula...

Authors: Rungroj Krittayaphong, Pansak Laksanabunsong, Adisak Maneesai, Pairash Saiviroonporn, Suthipol Udompunturak and Vithaya Chaithiraphan

Evaluating the systemic right ventricle by CMR: the importance of consistent and reproducible delineation of the cavity

The method used to delineate the boundary of the right ventricle (RV), relative to the trabeculations and papillary muscles in cardiovascular magnetic resonance (CMR) ventricular volume analysis, may matter mo...

Authors: Michiel M Winter, Flip JP Bernink, Maarten Groenink, Berto J Bouma, Arie PJ van Dijk, Willem A Helbing, Jan GP Tijssen and Barbara JM Mulder

Vascular function assessed with cardiovascular magnetic resonance predicts survival in patients with advanced chronic kidney disease

Increased arterial stiffness is associated with mortality in patients with chronic kidney disease. Cardiovascular magnetic resonance (CMR) permits assessment of the central arteries to measure aortic function.

Authors: Patrick B Mark, Arthur Doyle, Kevin G Blyth, Rajan K Patel, Robin AP Weir, Tracey Steedman, John E Foster, Henry J Dargie and Alan G Jardine

Cystic adventitial disease of the popliteal artery: features on 3T cardiovascular magnetic resonance

Cystic adventitial disease (CAD) of the popliteal artery is a rare vascular disease of unknown etiology in which a mucin-containing cyst develops in the adventitial layer of the artery. We report the case of a...

Authors: Anderanik Tomasian, Chi Lai, J Paul Finn, Hugh Gelabert and Mayil S Krishnam

Cardiovascular magnetic resonance of the charcoal heart

We report a case of malignant melanoma metastasis to the heart presenting as complete heart block. The highlight of the case is to demonstrate that silent cardiac metastasis is not uncommon and CMR has the pot...

Authors: Vikas K Rathi, Ronald B Williams, June Yamrozik, Howard Grill and Robert WW Biederman

Routine evaluation of left ventricular diastolic function by cardiovascular magnetic resonance: A practical approach

Cardiovascular magnetic resonance (CMR) has excellent capabilities to assess ventricular systolic function. Current clinical scenarios warrant routine evaluation of ventricular diastolic function for complete ...

Authors: Vikas K Rathi, Mark Doyle, June Yamrozik, Ronald B Williams, Ketheswaram Caruppannan, Craig Truman, Diane Vido and Robert WW Biederman

Standardized cardiovascular magnetic resonance imaging (CMR) protocols, society for cardiovascular magnetic resonance: board of trustees task force on standardized protocols

1. General techniques

Authors: Christopher M Kramer, Jorg Barkhausen, Scott D Flamm, Raymond J Kim and Eike Nagel

Cardiovascular magnetic resonance of pulmonary artery growth and ventricular function after Norwood procedure with Sano modification

For hypoplastic left heart syndrome (HLHS), there have been concerns regarding pulmonary artery growth and ventricular dysfunction after first stage surgery consisting of the Norwood procedure modified with a ...

Authors: D Scott Lim, Benjamin B Peeler, G Paul Matherne and Christopher M Kramer

Strain-encoding cardiovascular magnetic resonance for assessment of right-ventricular regional function

Tissue tagging by cardiovascular magnetic resonance (CMR) is a comprehensive method for the assessment of cardiac regional function. However, imaging the right ventricle (RV) using this technique is problemati...

Authors: Amr Youssef, El-Sayed H Ibrahim, Grigorios Korosoglou, M Roselle Abraham, Robert G Weiss and Nael F Osman

Role of cardiovascular magnetic resonance imaging in arrhythmogenic right ventricular dysplasia

Arrhythmogenic right ventricular dysplasia (ARVD) is a genetic cardiomyopathy characterized clinically by ventricular arrhythmias and progressive right ventricular (RV) dysfunction. The histopathologic hallmar...

Authors: Aditya Jain, Harikrishna Tandri, Hugh Calkins and David A Bluemke

Differences in carotid arterial morphology and composition between individuals with and without obstructive coronary artery disease: A cardiovascular magnetic resonance study

We sought to determine differences with cardiovascular magnetic resonance (CMR) in the morphology and composition of the carotid arteries between individuals with angiographically-defined obstructive coronary ...

Authors: Hunter R Underhill, Chun Yuan, James G Terry, Haiying Chen, Mark A Espeland, Thomas S Hatsukami, Tobias Saam, Baocheng Chu, Wei Yu, Minako Oikawa, Norihide Takaya, Vasily L Yarnykh, Robert Kraft, J Jeffrey Carr, Joseph Maldjian, Rong Tang…

Multidirectional flow analysis by cardiovascular magnetic resonance in aneurysm development following repair of aortic coarctation

Aneurysm formation is a life-threatening complication after operative therapy in coarctation. The identification of patients at risk for the development of such secondary pathologies is of high interest and re...

Authors: Alex Frydrychowicz, Raoul Arnold, Daniel Hirtler, Christian Schlensak, Aurelien F Stalder, Jürgen Hennig, Mathias Langer and Michael Markl

Accelerated CMR using zonal, parallel and prior knowledge driven imaging methods

Accelerated imaging is highly relevant for many CMR applications as competing constraints with respect to spatiotemporal resolution and tolerable scan times are frequently posed. Three approaches, all involvin...

Authors: Sebastian Kozerke and Sven Plein

Noninvasive assessment of coronary vasodilation using cardiovascular magnetic resonance in patients at high risk for coronary artery disease

Impaired coronary vasodilation to both endothelial-dependent and endothelial-independent stimuli have been associated with atherosclerosis. Direct measurement of coronary vasodilation using x-ray angiography o...

Authors: Patricia K Nguyen, Craig Meyer, Jan Engvall, Phillip Yang and Michael V McConnell

Measurement of left ventricular dimensions with contrast-enhanced three-dimensional cine imaging facilitated by k-t SENSE

To compare three-dimensional (3D) k-t sensitivity encoded (k-t SENSE) cine cardiovascular magnetic resonance (CMR), before and after contrast administration, against standard 2D imaging for the assessment of left...

Authors: Neil Maredia, Sebastian Kozerke, Abdul Larghat, Nik Abidin, John P Greenwood, Peter Boesiger and Sven Plein

Regional assessment of left ventricular torsion by CMR tagging

To introduce a standardized method for calculation of left ventricular torsion by CMR tagging and to determine the accuracy of torsion analysis in regions using an analytical model.

Authors: Iris K Rüssel, Marco J Götte, Joost P Kuijer and J Tim Marcus

Cardiovascular magnetic resonance features of caseous calcification of the mitral annulus

We present two cases of caseous calcification of the mitral annulus studied by Cardiovascular Magnetic Resonance; the diagnostic feature of this rare cardiac mass are described.

Authors: Lorenzo Monti, Eva Renifilo, Manuel Profili and Luca Balzarini

Feasibility of single breath-hold left ventricular function with 3 Tesla TSENSE acquisition and 3D modeling analysis

A single breath-hold evaluation of ventricular function would allow assessment in cases where scan time or patient tolerance is limited. Spatiotemporal acceleration techniques such as TSENSE decrease cardiovas...

Authors: Alistair A Young, Brett R Cowan, Stefan O Schoenberg and Bernd J Wintersperger

Ventricular Assist Device implant (AB 5000) prototype cannula: In vitro assessment of MRI issues at 3-Tesla

To evaluate MRI issues at 3-Tesla for a ventricular assist device (VAD).

Authors: Frank G Shellock and Samuel Valencerina

Rapid phase-modulated water-excitation steady-state free precession for fat-suppressed cine cardiovascular MR

The purpose of this article is to describe a steady-state free precession (SSFP) sequence for fat-suppressed cine cardiovascular magnetic resonance (CMR). A rapid phase-modulated binomial water-excitation (WE)...

Authors: Hung-Yu Lin, Subha V Raman, Yiu-Cho Chung and Orlando P Simonetti

Time course of eosinophilic myocarditis visualized by CMR

We report the diagnostic potential of cardiovascular magnetic resonance (CMR) to visualize the time course of eosinophilic myocarditis upon successful treatment. A 50-year-old man was admitted with a progressi...

Authors: Kurt Debl, Behrus Djavidani, Stefan Buchner, Florian Poschenrieder, Norbert Heinicke, Stefan Feuerbach, Günter Riegger and Andreas Luchner

Late Gadolinium Enhancement of the right ventricular myocardium: Is it really different from the left ?

It has been suggested that, in late gadolinium enhancement, the signal of right ventricular myocardium is nulled at a shorter inversion time than the left. While we initially made the same observation, we beli...

Authors: Lars Grosse-Wortmann, Christopher K Macgowan, Logi Vidarsson and Shi-Joon Yoo

Relation between myocardial edema and myocardial mass during the acute and convalescent phase of myocarditis – a CMR study

Myocardial edema is a substantial feature of the inflammatory response in human myocarditis. The relation between myocardial edema and myocardial mass in the course of healing myocarditis has not been systemat...

Authors: Anja Zagrosek, Ralf Wassmuth, Hassan Abdel-Aty, André Rudolph, Rainer Dietz and Jeanette Schulz-Menger

Myocardial first-pass perfusion cardiovascular magnetic resonance: history, theory, and current state of the art

In less than two decades, first-pass perfusion cardiovascular magnetic resonance (CMR) has undergone a wide range of changes with the development and availability of improved hardware, software, and contrast a...

Authors: Bernhard L Gerber, Subha V Raman, Krishna Nayak, Frederick H Epstein, Pedro Ferreira, Leon Axel and Dara L Kraitchman

Quantitative characterization of myocardial infarction by cardiovascular magnetic resonance predicts future cardiovascular events in patients with ischemic cardiomyopathy

Cardiovascular magnetic resonance (CMR) can provide quantitative data of the myocardial tissue utilizing high spatial and temporal resolution along with exquisite tissue contrast. Previous studies have correla...

Authors: Hajime Yokota, Shahriar Heidary, Chandra K Katikireddy, Patricia Nguyen, John M Pauly, Michael V McConnell and Phillip C Yang

Mapping of mitral regurgitant defects by cardiovascular magnetic resonance in moderate or severe mitral regurgitation secondary to mitral valve prolapse

In mitral valve prolapse, determining whether the valve is suitable for surgical repair depends on the location and mechanism of regurgitation. We assessed whether cardiovascular magnetic resonance (CMR) could...

Authors: Ruvin S Gabriel, Andrew J Kerr, Owen C Raffel, Ralph A Stewart, Brett R Cowan and Christopher J Occleshaw

Myocardial ischemia in the absence of epicardial coronary artery disease in Friedreich's ataxia

We present the first in vivo detection of microvascular abnormality in a patient with Friedreich's ataxia (FA) without epicardial coronary artery disease using cardiac magnetic resonance (CMR). The patient had ex...

Authors: Subha V Raman, Jennifer A Dickerson and Roula Al-Dahhak

Imaging myocardial carcinoid with T2-STIR CMR

We used T2-STIR (Short Tau Inversion Recovery) cardiovascular magnetic resonance to demonstrate carcinoid tumor metastases to the heart and liver in a 64-year-old woman with a biopsy-proven ileal carcinoid tum...

Authors: William A Schiavone, Christopher Baker and Sanjay K Prasad

Correction of misaligned slices in multi-slice cardiovascular magnetic resonance using slice-to-volume registration

A popular technique to reduce respiratory motion for cardiovascular magnetic resonance is to perform a multi-slice acquisition in which a patient holds their breath multiple times during the scan. The feasibil...

Authors: Adam G Chandler, Richard J Pinder, Thomas Netsch, Julia A Schnabel, David J Hawkes, Derek LG Hill and Reza Razavi

Combined chelation therapy in thalassemia major for the treatment of severe myocardial siderosis with left ventricular dysfunction

In thalassemia major (TM), severe cardiac siderosis can be treated by continuous parenteral deferoxamine, but poor compliance, complications and deaths occur. Combined chelation therapy with deferiprone and de...

Authors: Mark A Tanner, Renzo Galanello, Carlo Dessi, Gillian C Smith, Mark A Westwood, Annalisa Agus, Martina Pibiri, Sunil V Nair, J Malcolm Walker and Dudley J Pennell

Multi-center transferability of a breath-hold T2 technique for myocardial iron assessment

Cardiac iron overload is the leading cause of death in thalassemia major and is usually assessed using myocardial T2* measurements. Recently a cardiovascular magnetic resonance (CMR) breath-hold T2 sequence ha...

Authors: Taigang He, Paul Kirk, David N Firmin, Wynnie M Lam, Winnie CW Chu, Wing-Yan Au, Godfrey CF Chan, Ru San Tan, Ivy Ng, Selen Biceroglu, Yesim Aydinok, Mark A Fogel, Alan R Cohen and Dudley J Pennell

Uncomplicated obesity is associated with abnormal aortic function assessed by cardiovascular magnetic resonance

Obese subjects with insulin resistance and hypertension have abnormal aortic elastic function, which may predispose them to the development of left ventricular dysfunction. We hypothesised that obesity, uncomp...

Authors: Monique R Robinson, Michaela Scheuermann-Freestone, Paul Leeson, Keith M Channon, Kieran Clarke, Stefan Neubauer and Frank Wiesmann

Cardiac structure and function during ageing in energetically compromised Guanidinoacetate N-methyltransferase (GAMT)-knockout mice – a one year longitudinal MRI study

High-resolution magnetic resonance imaging (cine-MRI) is well suited for determining global cardiac function longitudinally in genetically or surgically manipulated mice, but in practice it is seldom used to i...

Authors: Jürgen E Schneider, Lee-Anne Stork, Jordana T Bell, Michiel ten Hove, Dirk Isbrandt, Kieran Clarke, Hugh Watkins, Craig A Lygate and Stefan Neubauer

Angiographic correlations of patients with small vessel disease diagnosed by adenosine-stress cardiac magnetic resonance imaging

Cardiac magnetic resonance imaging (CMR) with adenosine-stress myocardial perfusion is gaining importance for the detection and quantification of coronary artery disease (CAD). However, there is little knowled...

Authors: Guenter Pilz, Markus Klos, Eman Ali, Berthold Hoefling, Roland Scheck and Peter Bernhardt

Accuracy of electrocardiographic criteria for atrial enlargement: validation with cardiovascular magnetic resonance

Anatomic atrial enlargement is associated with significant morbidity and mortality. However, atrial enlargement may not correlate with clinical measures such as electrocardiographic (ECG) criteria. Past studie...

Authors: Connie W Tsao, Mark E Josephson, Thomas H Hauser, T David O'Halloran, Anupam Agarwal, Warren J Manning and Susan B Yeon

Assessment of myocardial infarction in mice by Late Gadolinium Enhancement MR imaging using an inversion recovery pulse sequence at 9.4T

To demonstrate the feasibility of using an inversion recovery pulse sequence and to define the optimal inversion time (TI) to assess myocardial infarction in mice by late gadolinium enhancement (LGE) MRI at 9....

Authors: Catherine Chapon, Amy H Herlihy and Kishore K Bhakoo

Delayed contrast enhancement cardiac magnetic resonance imaging in trastuzumab induced cardiomyopathy

Trastuzumab (Herceptin), an antagonist to the human epidermal growth factor 2 (HER2) receptor significantly decreases the rates of breast cancer recurrence and mortality by 50%. Despite therapeutic benefits, t...

Authors: Nazanin Fallah-Rad, Matthew Lytwyn, Tielan Fang, Iain Kirkpatrick and Davinder S Jassal

Anomalous origin of the left circumflex coronary artery from the pulmonary artery. A very rare congenital anomaly in an adult patient diagnosed by cardiovascular magnetic resonance

Here we report for the first time on the diagnostic potential of cardiovascular magnetic resonance (CMR) to delineate the proximal course of an anomalous left circumflex coronary artery (LCX) originating from ...

Authors: Grigorios Korosoglou, Gerd Ringwald, Evangelos Giannitsis and Hugo A Katus

Utility of Cardiac Magnetic Resonance to assess association between admission hyperglycemia and myocardial damage in patients with reperfused ST-Segment Elevation Myocardial Infarction

to investigate the association between admission hyperglycemia and myocardial damage in patients with ST-segment elevation myocardial infarction (STEMI) using Cardiac Magnetic Resonance (CMR).

Authors: Alexandre Cochet, Marianne Zeller, Alain Lalande, Isabelle L'Huillier, Paul M Walker, Claude Touzery, Bruno Verges, Jean-Eric Wolf, François Brunotte and Yves Cottin

Journal of Cardiovascular Magnetic Resonance: Open access in 2008

Authors: Dudley J Pennell