Table 1 Values of left ventricle end-diastolic, end-systolic volumes, stroke volume, ejection fraction and heart rate in normal rats at rest and during incremental doses of dobutamine (mean ± SD)

LVEDV (μl)

609 ± 73

604 ± 50

616 ± 67

607 ± 73

LVESV (μl)

158 ± 36

117 ± 29

76 ± 24 (*†)

56 ± 12 (*†)

Stroke volume (μl)

451 ± 54

487 ± 47

540 ± 59

551 ± 78

Ejection fraction(%)

74.2 ± 4.4

80.6 ± 4.6 (*)

87.7 ± 3.7 (*†)

90.7 ± 2.4 (*†)

Heart rate (bpm)

325 ± 31

337 ± 38

350 ± 29

386 ± 33

Cardiac output (ml/min)

147 ± 17

164 ± 18

189 ± 17 (*)

213 ± 26 (*)