|
Trait a
|
Factor b
|
Coefficient estimate
|
95% CI
|
P-value
|
|---|
|
BW
|
Sex
|
-5.13
|
[-6.72, -3.54]
|
<0.0001
|
| |
Genotype
|
-2.40
|
[-4.3, -0.49]
|
<0.0001
|
| |
Time
|
-
|
-
|
<0.0001
|
| |
4 months
|
6.34
|
[4.86, 7.82]
|
<0.0001
|
| |
8 months
|
8.28
|
[6.9, 9.66]
|
<0.0001
|
| |
12 months
|
11.73
|
[10.33, 13.13]
|
<0.0001
|
| |
Genotype*Time
|
-
|
-
|
0.0003
|
| |
Genotype*4 months
|
-1.52
|
[-3.55, 0.52]
|
0.1415
|
| |
Genotype*8 months
|
-2.60
|
[-4.56, -0.64]
|
0.0102
|
| |
Genotype*12 months
|
-4.79
|
[-6.88, -2.69]
|
<0.0001
|
|
LVM
|
BW
|
0.88
|
[-0.06, 1.81]
|
<0.0001
|
| |
Sex
|
-4.50
|
[-13.36, 4.35]
|
0.2636
|
| |
Genotype
|
-8.85
|
[-16.91, -0.78]
|
0.7443
|
| |
Time
|
-
|
-
|
0.0003
|
| |
4 months
|
15.35
|
[7.9, 22.8]
|
0.0001
|
| |
8 months
|
18.55
|
[10.27, 26.84]
|
<0.0001
|
| |
12 months
|
19.29
|
[8.84, 29.74]
|
0.0005
|
|
EF
|
Sex
|
1.06
|
[-2.55, 4.66]
|
0.4924
|
| |
Genotype
|
3.46
|
[-0.02, 6.94]
|
0.0334
|
| |
Time
|
-
|
-
|
0.0027
|
| |
4 months
|
-1.43
|
[-5.58, 2.72]
|
0.4947
|
| |
8 months
|
-5.42
|
[-9.44, -1.4]
|
0.009
|
| |
12 months
|
-7.30
|
[-11.55, -3.06]
|
0.001
|
|
Heart rate
|
Sex
|
-48.49
|
[-74.64, -22.33]
|
0.1958
|
| |
Genotype
|
-42.08
|
[-67.96, -16.2]
|
0.698
|
| |
Time
|
-
|
-
|
0.0519
|
| |
4 months
|
4.99
|
[-17.61, 27.58]
|
0.6611
|
| |
8 months
|
-23.16
|
[-44.79, -1.54]
|
0.0362
|
| |
12 months
|
-20.67
|
[-43.49, 2.15]
|
0.0751
|
| |
Sex*Genotype
|
73.26
|
[35.93, 110.6]
|
0.0004
|
|
dV/dtmax.EDV-1
|
Sex
|
0.002
|
[0.001, 0.004]
|
0.0048
|
| |
Genotype
|
0.000
|
[-0.001, 0.002]
|
0.8454
|
| |
Time
| | |
0.0009
|
| |
4 months
|
-0.001
|
[-0.003, 0.001]
|
0.2688
|
| |
8 months
|
-0.003
|
[-0.005, -0.001]
|
0.0017
|
| |
12 months
|
-0.004
|
[-0.005, -0.002]
|
0.0004
|
- a Traits for which at least one factor in the model had significant (P < 0.01) effects.
- b Estimated effects of KO compared to WT (baseline) for Genotype, female compared to male (baseline) for Sex, and trait values at 4 months, 8 months, and 12 months compared to trait values at 6 weeks (baseline) for Time (3df test)
