Figure 1

There is a sharp boundary between the healed infarct (I) and viable myocytes (M). At 7–8 weeks following coronary artery occlusion/reperfusion. At the edge of infarction in control animals few sparse thin-walled vessels (arrows), thick-walled vessels (arrowheads) and degenerated myocytes are shown (top left). In contrast, a treated HGF heart showed an irregular healed infarct (I) borders (top right). The edge of the scar contains numerous thin-walled blood vessels (arrows). Top panels:_Masson trichrome stain. Bottom panels: biotinylated Bandeiria simplicifolia isolectin B₄. Calibration bars = 45 microns.