Table 2 Demographics and Plaque Characteristics
|  | Volunteers (n = 14) Mean ± SD or % | Patients (n = 13) Mean ± SD or % | p-value* |
|---|---|---|---|
I. Demographics and Risk Factors | Â | Â | Â |
Age [years] | 32.6 ± 11.7 | 70.5 ± 8.3 | P < .001 |
Body Mass Index | 23.8 ± 2.3 | 24.1 ± 1.9 | n.s. |
Male Sex [%] | 50% | 69.2% | n.s. |
Coronary Artery Disease [%] | 0% | 46.2% | P < .05 |
Hypertension [%] | 0% | 61.5% | P < .05 |
Hypercholesterolemia [%] | 7.1% | 69.2% | P < .05 |
Diabetes [%] | 0% | 30.8% | P < .05 |
Family History of CVD [%] | 21.4% | 23.1% | n.s. |
Active Smoker [%] | 57.1% | 15.4% | P < .05 |
II. Plaque Characteristics | Â | Â | Â |
Mean Lumen Area CCA [mm2] | 41.92 ± 17.55 | 41.17 ± 14.36 | n.s. |
Mean Lumen Area ICA [mm2] | 34.91 ± 13.41 | 16.63 ± 7.26 | P < .05 |
Mean Wall Area CCA [mm2] | 17.47 ± 8.05 | 43.80 ± 15.38 | P < .001 |
Mean Wall Area ICA [mm2] | 14.77 ± 6.80 | 33.80 ± 14.07 | P < .05 |
Mean Total Vessel Area CCA [mm2] | 59.39 ± 23.95 | 84.97 ± 28.44 | P < .05 |
Mean Total Vessel Area ICA [mm2] | 49.69 ± 18.22 | 50.44 ± 16.62 | n.s. |
Mean NWI CCA | 0.30 ± 0.06 | 0.50 ± 0.04 | P < .001 |
Mean NWI ICA | 0.30 ± 0.08 | 0.66 ± 0.12 | P < .001 |
Lipid-Rich Necrotic Core** [%] | 3.7% | 76.9% | P < .05 |
Calcification** [%] | 0% | 73.1% | P < .05 |
Hemorrhage** [%] | 0% | 46.2% | P < .05 |