Reduced peripheral arterial blood flow with preserved cardiac output during submaximal bicycle exercise in elderly heart failure

Table 1 Demographic data (mean ± standard deviation)

	Healthy (n = 13)	Heart Failure (n = 12)	p-value
Male, n(%)	6(46%)	6(50%)	0.85
Age (years)	67 ± 5	70 ± 8	0.29
Weight (kg)	76 ± 11	81 ± 14	0.41
Height (cm)	171 ± 10	169 ± 10	0.5
BSA (m ² )	1.9 ± 0.2	1.9 ± 0.2	0.64
LVEF(%)	66 ± 7	48 ± 25	0.04*
Diabetes, n(%)	0(0%)	1(8%)	0.48
Hypertension, n (%)	0(0%)	8(67%)	0.001*
Hypercholesterolemia	0(0%)	8(67%)	0.001*
Prior myocardial infarction	0(0%)	4(33%)	0.04*
COPD/Asthma	0(0%)	2(17%)	0.22
Medication, n(%)
Betablocker	0(0%)	8(67%)	<0.001*
ACE inhibitor	0(0%)	6(50%)	0.01*
ARB	0(0%)	2(17%)	0.22
Calcium channel blocker	1(8%)	3(25%)	0.32
Digoxin	0(0%)	2(17%)	0.22
Hydralazine	0(0%)	1(8%)	0.48
Nitrate	0(0%)	2(17%)	0.22
Aspirin/NSAID	9(69%)	6(50%)	0.43
Diuretic	0(0%)	6(50%)	0.01*
Statin	0(0%)	5(42%)	0.01*
Calcium supplement	5(38%)	2(17%)	0.38
Prior hormone replacement therapy	1(8%)	0(0%)	1
Hemoglobin (g/dl)	14.9 ± 1.7	13.1 ± 1.4	0.02*
BNP	20 ± 12	118 ± 132	0.06
Serum sodium level	143 ± 2	142 ± 2	0.61
* = p < 0.05

Abbreviation: ACE = Angiotensin converting enzyme; ARB = Angiotensin II receptor blocker; BMI = Body mass index; BNP = B-Type natriuretic peptide; BSA = Body surface area; BUN = Blood urea nitrogen; COPD = chronic obstructive airway disease; FBS = Fasting blood sugar; LVEF = left ventricular ejection fraction; NSAID = Non-steroid anti-inflammatory drug

ISSN: 1532-429X