Skip to content


Open Access

CMR evaluation in patients with high grade ventricular arrhythmias

  • Antonio Bernardini1,
  • Agostino Meduri2, 3,
  • Luigi Natale2,
  • Carlo Liguori2,
  • Riccardo Fenici2,
  • Donatella Brisinda2 and
  • Lorenzo Bonomo2
Journal of Cardiovascular Magnetic Resonance200911(Suppl 1):P205

Published: 28 January 2009


Ventricular ArrhythmiaWall Motion AbnormalityLeave Bundle Branch BlockRight Bundle Branch BlockPremature Ventricular Complex


To assess by cardiac-MR the prevalence of myocardial alterations in arrhythmic patients.

Materials and methods

43 patients with non ischemic ventricular arrhythmias. Premature ventricular complexes had left bundle branch block morphology (LBBB) in 29 cases, in 7 a right bundle branch block contour (RBBB) and 7 had polymorphic patterns(PV). US was negative in 78.4% of patients, while CMR was negative in only 13% of patients. Studies were performed on a 1.5 MR scanner with Cine sequences (Fastcard or FIESTA), bb-FSE and IR-prep FGRE 15 minutes after injection of 0.2 mmol/Kg of Gd-DTPA.


CMR found a high prevalence of morphological, signal intensity and functional myocardial abnormalities. RV dilatation was found in 85% of patients with PV arrhytmias, 48.3% of patients with LBBB morphology, 12.5% of patients with RBBB morphology. LV dilatation was present in 28.6%, 25% and 24.1% of patients with LBBB, PV and RBBB type arrhytmias respectively. RV wall motion abnormalities were identified in 50% and 36.7% of patients with PV and LBBB pattern respectively while LV motion abnormalities in 25% and 10.3%. Free wall RV signal/thickness abnormalities were found in 23.3% of patients; LV signal abnormalities were found in 11.6% of patients.

Seven patients underwent myocardial biopsy: 5 positive for myocarditis, 1 positive for ARVD, one had a negative biopsy.


In patients with primary ventricular arrhythmias MR documented high prevalence (87%) of morphological, signal intensity and wall motion abnormalities even with negative echocardiogram.

Authors’ Affiliations

"G. Mazzini" Hospital – ASL Teramo, Teramo, Italy
Università Cattolica del Sacro Cuore – Policlinico A. Gemelli, Rome, Italy
Università Cattolica del Sacro Cuore, Rome, Italy


© Bernardini et al; licensee BioMed Central Ltd. 2009

This article is published under license to BioMed Central Ltd.