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  • Open Access

Contrast enhanced MRI and MR coronary angiography (MRCA) as one stop shop in patients with untreated myocardial infarction

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Journal of Cardiovascular Magnetic Resonance200911 (Suppl 1) :P280

  • Published:


  • Coronary Angiography
  • Short Axis
  • Conventional Coronary Angiography
  • Signa Excite
  • Blinded Reader


To define MRI role in patients with myocardial infarction not treated by PCI.

Methods and materials

24 pts (17 males, 7 females) with myocardial infarction (7 anterior, 9 lateral, 8 inferior), untreated by PCI, underwent MRI within three weeks after infarction. MRI was performed on a 1.5 T scanner (GE Signa Excite) with this protocol:

1) Triple-IR FSE sequence short axis for edema;

2) Fiesta sequences on short, horizontal and vertical long axes, for regional and global systolic function;

3) FGR-ET short axis sequence for first pass;

4) IR-FGRE sequence on short, horizontal and vertical long axes, for infarct size.

5) Before delayed imaging, MRCA with breath-hold 3D Fiesta VCATS technique was obtained. MRCA was compared with the gold standard conventional coronary angiography (CA), performed within 24–48 h.


MRCA was scored with a 3 points scale (0 = good, 1 = sufficient, 2 = poor) by 2 blinded readers; 3 exams were excluded as pts could not hold their breath. MRCA showed 11 severe stenoses (>50%) and 9 occlusions, with 1 exam not evaluable for poor quality; CA showed severe stenoses in 14 and 7 occlusions. Collaterals and retrograde filling were present in 2 occlusions at CA; in these 2 cases DE at MRI was ≤50%. DE and FP defects distribution always showed correlation with the diseased vessel. MRCA showed 100% sensitivity, 78.6% specificity, 70% PPV, 100% NPV.


In pts not treated by primary or rescue PCI, MRCA can rule out occlusion and/or significant stenosis; the correlation with segmental distribution of DE is excellent.

Authors’ Affiliations

Università Cattolica del Sacro Cuore – Policlinico A. Gemelli, Rome, Italy
"G. Mazzini" Hospital – ASL Teramo, Teramo, Italy


© Liguori et al; licensee BioMed Central Ltd. 2009

This article is published under license to BioMed Central Ltd.