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Table 5 Performance of cine-CMR Indices in Relation to Diastolic Dysfunction Severity - Diastolic Filling Rates

From: Impact of diastolic dysfunction severity on global left ventricular volumetric filling - assessment by automated segmentation of routine cine cardiovascular magnetic resonance

 

Threshold

Sensitivity

Specificity

Accuracy

Positive

Predictive

Value

Negative

Predictive

Value

GRADE 1 (mild)

      

   Peak Filling Rate

344 ml/sec†

5% (1/21)

83% (33/40)

56% (34/61)

13% (1/8)

62% (33/53)

   Normalized Peak Filling Rate

4.02/sec†

0% (0/21)

83% (33/40)

54% (33/61)

0% (0/7)

61% (33/54)

GRADE 2 (moderate)

      

   Peak Filling Rate

344 ml/sec

7% (3/45)

83% (33/40)

42% (36/85)

30% (3/10)

44% (33/75)

   Normalized Peak Filling Rate

4.02/sec

9% (4/45)

83% (33/40)

44% (37/85)

36% (4/11)

45% (33/74)

GRADE 3 (severe)

      

   Peak Filling Rate

344 ml/sec

56% (5/9)

83% (33/40)

78% (38/49)

42% (5/12)

89% (33/37)

   Normalized Peak Filling Rate

4.02/sec

67% (6/9)

83% (33/40)

80% (39/49)

46% (6/13)

91% (33/36)

  1. * Threshold of 77% diastole (to recover 80% stroke volume) based on previously established normative cutoff [15]
  2. † Matched to achieve equivalent specificity vs. DVR80