Nasal continuous positive airway pressure improves myocardial perfusion reserve and endothelial-dependent vasodilation in patients with obstructive sleep apnea

Table 5 Cardiac Structure and Function, Myocardial Perfusion Reserve and Coronary Artery Vasoreactivity by Magnetic Resonance Imaging

	Baseline			Treatment			Before vs. After Treatment Pairwise Comparison (p value)
	Active	Sham	p	Active	Sham	p	Active	Sham
LV Mass	106.1 ± 28.9	108.3 ± 23.6	0.86	111.34 ± 39.8	118.4 ± 25.0	0.66	0.36	0.18
LV Mass/BSA	52.2 ± 11.4	49.3 ± 7.9	0.54	56.6 ± 18.4	69.9 ± 32.2	0.98	0.38	0.15
RVEDV	161.1 ± 28.6	171.8 ± 35.4	0.49	165.8 ± 38.1	181.6 ± 54.2	0.48	0.40	0.40
RVEDV/BSA	79.7 ± 13.0	79.1 ± 15.8	0.93	81.7 ± 79.4	82.6 ± 22.5	0.92	0.45	0.53
LVEDV	148.3 ± 32	158.3 ± 31.1	0.51	151.1 ± 30.5	163.4 ± 38.7	0.46	0.63	0.39
LVEDV/BSA	73.0 ± 13.5	72.3 ± 9.6	0.88	74.7 ± 13.4	74.4 ± 14.2	0.96	0.47	0.57
RV EF	58.9 ± 6.9	56.7 ± 9.0	0.57	55.5 ± 5.7	54.0 ± 11.4	0.80	0.26	0.43
LV EF	68.9 ± 7.1	67.4 ± 8.2	0.69	71.5 ± 4.6	65.1 ± 7.5	0.04	0.34	0.31
MPR	1.5 ± 0.5	2.0 ± 1.2	0.38	3.0 ± 1.3	2.5 ± 1.1	0.49	0.02	0.38
Change in CSA RCA, %	14+8	20 ± 10	0.16	18 ± 15	15 ± 8	0.58	0.46	0.23

LV: left ventricle, BSA: body surface area, RV: right ventricle, EDV: end diastolic volume, EF: ejection fraction, MPR: myocardial perfusion reserve, CSA: cross sectional area, RCA: right coronary artery

ISSN: 1532-429X