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Table 1 European Society of Cardiology guidelines for cardiac resynchronization therapy (2010 Update).*

From: Cardiac resynchronization therapy guided by cardiovascular magnetic resonance

Recommendation Patient population Class Level
Sinus rhythm    
CRT preferentially by CRT-D is recommended to reduce morbidity or to prevent disease progression NYHA class II I A
  LVEF ≤ 35%, QRS ≥ 150 ms   
CRT-P/CRT-D is recommended to reduce morbidity and mortality NYHA class III/IV I A
  LVEF ≤ 35%, QRS ≥ 120 ms   
  Optimal medical therapy   
Atrial fibrillation    
CRT-P/CRT-D should be considered to reduce morbidity NYHA class III/IV IIa B
  LVEF ≤ 35%, QRS ≥ 130 ms   
  Permanent dependency induced by AV nodal ablation   
CRT-P/CRT-D should be considered to reduce morbidity NYHA class III/IV IIa C
  LVEF ≤ 35%, QRS ≥ 130 ms   
  Slow ventricular rate and frequent pacing   
Concomitant Class I pacemaker indication    
CRT-P/CRT-D is recommended to reduce morbidity NYHA class III/IV I B
  LVEF ≤ 35%, QRS ≥ 120 ms   
CRT-P/CRT-D is recommended to reduce morbidity NYHA class III/IV IIa C
  LVEF ≤ 35%, QRS < 120 ms   
CRT-P/CRT-D is recommended to reduce morbidity NYHA class II IIb C
  LVEF ≤ 35%, QRS < 120 ms   
  1. *Recommendations according to presence of sinus rhythm, atrial fibrillation or concomitant conventional pacemaker indications, taken from Dickstein K, et al. [126] Class and level of evidence is shown in the columns. CRT-P = cardiac resynchronization therapy pacing; CRT-D = cardiac resynchronization therapy - defibrillation.