First-pass perfusion CMR two days after infarction predicts severity of functional impairment six weeks later in the rat heart

Table 1 In vivo measurements of rat heart morphology and function before and at 2, 8 and 42 days after infarction (n = 27)

	Pre	2 days	8 days	42 days
Left ventricular mass (mg)	492 ± 35	543 ± 18*	571 ± 15*	586 ± 16*^#
End diastolic volume (μl)	265 ± 12	282 ± 11	395 ± 15*^#	428 ± 24*^#+
End systolic volume (μl)	55 ± 8	108 ± 5*	154 ± 13*^#	185 ± 19*^#+
Stroke volume (μl)	210 ± 9	174 ± 8*	241 ± 7^#	243 ± 11^#
Ejection fraction (%)	80 ± 2	62 ± 1*	62 ± 2*	58 ± 2*^#+
Akinetic myocardium (mm²)	-	16 ± 4*	23 ± 5*^#	28 ± 6*^#+
Akinetic myocardium (%)	-	9 ± 2*	10 ± 2*	11 ± 2*
Heart rate (bpm)	404 ± 11	361 ± 9	344 ± 27	346 ± 26
Cardiac output (ml/min)	85 ± 5	61 ± 3*	83 ± 3^#	80 ± 3^#
Weight (g)	234 ± 11	214 ± 3	230 ± 5	245 ± 19

* p < 0.05 compared with pre-infarction. ^#p < 0.05 compared with 2 days. ⁺ p < 0.05 compared with 8 days,

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