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Differences between early versus late correction of Tetralogy of Fallot (TOF) in cardiac Magnetic Resonance (CMR)
Journal of Cardiovascular Magnetic Resonance volume 13, Article number: P193 (2011)
Tetralogy of Fallot can be repaired with low mortality and most patients reach adulthood. Nevertheless the optimal timing of surgery remains controversial.
To evaluate differences between early versus late correction of Tetralogy of Fallot (TOF) in cardiac Magnetic Resonance (CMR).
CMR was performed in 55 patients (20 male) using a 1.5T scanner. RV-volumes and pulmonary-regurgitant-fractions (PRF) were calculated from standard cine-sequences and flow-sensitive gradient-echo images, respectively. Scar tissue was quantified from Delayed Enhancement (DE) imaging. Patients were divided into two groups depending age at total repair (group 1≤1year, n=25; group2>1years, n=30).
In 50 patients (91%) RV image quality was diagnostic for quantification of RV DE. Patients of group 2 demonstrated with a significantly higher RV DE (p<0.05) compared to group 1. No differences were found in regard to LV DE, RV size and RV function.
Patients repaired <1 year show a lower amount of fibrous tissue in the RV. This might support the strategy of early repair.
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Grothoff, M., Hoffmann, J., Boegershausen, K. et al. Differences between early versus late correction of Tetralogy of Fallot (TOF) in cardiac Magnetic Resonance (CMR). J Cardiovasc Magn Reson 13, P193 (2011). https://doi.org/10.1186/1532-429X-13-S1-P193
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- Image Quality
- Lower Amount
- Cardiac Magnetic Resonance
- Optimal Timing