Skip to main content

Detection of myocardial oedema with the use of diffusion-weighted imaging in acute myocardial infarction


MR diffusion-weighted imaging is an important application for oedema detection in various tissues. Evaluation of the area at risk in reperfused acute myocardial infarction (AMI) is currently performed with STIR T2-weighted and LGE sequences.


The aim of the study was to find practical application for a new diffusion-weighted sequences in evaluation myocardial oedema and compare it with routinely used STIR-T2 techniques.


In preliminary study myocardial oedema in 15 patients (13 male) with STEMI within 2-4 days were evaluated .The CMR examination was performed on a 1,5 T scanner (Magnetom Avanto; Siemens; Germany; Erlangen;) using a 8-channel phased-array coil. The parameters of the diffusion-weighted EPI sequence (DWI) were as follows: slice thickness 10mm, repetition time (depending on patient breath cycle) 3-4s, echo time 78ms, bandwidth 1,736 Hz/Px. The DW sequence was ECG-gated and synchronized to the respiratory cycle using PACE technique. Each slice was acquired with b = 50 s/mm2, 400s/mm2 and 800 s/mm2 with three perpendicular directions of the diffusion gradient. DW, STIR T2-weighted and LGE images were obtained in 2-chamber, 4-chamber or short-axis planes. Images were analysed quantitatively, contrast to noise ratio (CNR) of high signal (oedema) to healthy myocardium (CNR1) and high signal to blood (CNR2) were calculated. For statistical analysis a non parametric Wilcoxon test with significance level of p<0,05 was used.


The CNR were significantly higher on DWI than on STIR T2-weighted images: CNR1 (22±7 vs 12±8 p= 0,004, respectively)and CNR2 (28±10 vs 21±9, p=0,02 , respectively).


Our study confirms DW EPI is feasible sequence for myocardial oedema detection with even better contrast to noise ratio than standard STIR T2 sequences.

Figure 1

Myocardial oedema in 2 chamber view evaluated by A) STIR T2-weighted image; B) DW EPI sequence

Author information



Corresponding author

Correspondence to Anna Kociemba.

Rights and permissions

This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Reprints and Permissions

About this article

Cite this article

Kociemba, A., Lanocha, M., Katulska, K. et al. Detection of myocardial oedema with the use of diffusion-weighted imaging in acute myocardial infarction. J Cardiovasc Magn Reson 13, P98 (2011).

Download citation


  • Acute Myocardial Infarction
  • Myocardial Oedema
  • Slice Thickness 10mm
  • Breath Cycle
  • Reperfused Acute Myocardial Infarction