Figure 6

MTC detects collagen and fibrin as seen by histology. A, Subtracted magnetization transfer image of a vessel segment with mural thrombus (hypointense; red line). B, Corresponding Masson’s trichrome staining for collagen detection. C, Corresponding immunohistochemical staining for fibrin detection. D-F, Segmented MTC (D), trichrome (E), and immunohistochemistry (F) images show the correlation between MTC and histological detection of protein (collagen and fibrin) in the thrombus. MTC: magnetization transfer contrast.