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Table 1 Cinical data

From: Characteristics of carotid atherosclerotic plaques of chronic lipid apheresis patients as assessed by In Vivo High-Resolution CMR - a comparative analysis

Parameter

Lipid apheresis group

Control group

p-value*

 

(n=16 patients)

(n=32 patients)

 

Age ± 1 SD [years]

63.5 ± 9,1

73.9 ± 9.2

<0.05

Male [%]

68,8%

84.4%

ns

Body Mass Index

26.5 ± 4.4

25.1 ± 5.3

ns

Established CAD [%]

100%

21.9%

<0.001

Risk Factors

Hypercholesterolemia [%]

100%

53.3%

0.008

Arterial Hypertension, [%]

75%

68.8%

ns

Active Nicotine Abuse [%]

6.3%

28.1%

ns

Former Nicotine Abuse [%]

50%

40.7%

ns

Diabetes Mellitus [%]

18.8%

21.9%

ns

Family History of CAD or CVD [%]

68.8%

34.4%

0.03

Serum Lipids

Total Cholesterol [mg/dl]

148.8 ± 37.7

200.8 ± 47.1

<0.001

Triglycerides [mg/dl]

139.1 ± 93.9

142.0 ± 73.5

ns

LDL [mg/dl]

94.7 ± 28.9

128.3 ± 35.8

<0.001

VLDL [mg/dl]

18.6 ± 7.9

22.4 ± 10.4

ns

HDL [mg/dl]

49.3 ± 12.7

48.2 ± 9.2

ns

LDL/HDL

2.0 ± 1.0

2.8 ± 0.8

0.008

Lipoprotein (a) [mg/dl]

59.9 ± 66.6

47.4 ± 49.4

ns

  1. Two-sided Fisher’s Exact Test or unpaired t-test; SD=Standard Deviation; CAD=Coronary Artery Disease; CVD=Cerebrovascular Disease (TIA or Stroke). Values for LDL and Lp (a) for the lipid apheresis group are given as mean levels calculated as proposed by Kroon et al. [25]. Other serum lipid levels for the lipid apheresis group are given as average of measurements before and after apheresis therapy.