Figure 2

CMRI of allografts hearts from the WkHt model on POD 47 (top panels, A-E) and the Non-WkHt model on POD 41 (lower panels, F-J). (A, F) in vivo T2* MRI; (B, G) tagging MRI at ED; (C, H) tagging MRI at ES; (D, I) circumferential strain (Ecc) maps derived from tagging MRI; and (E, J) ex vivo T2* MR Microscopy (MRM). The hypointensity regions/sports appeared in A, F, E and J result from MPIO-labeled monocytes/macrophages.