Table 1 MBV by MRI shows expected relationship to MBF by microspheres

Average

4.923

5.771

1.172

Stenosis

6.186

33.0

5.395

20.07

0.872

Remote

4.651

6.75

1.451

Flow from microspheres

Rest

Stress

MBF (ml/min/g)

% Flow reduction (Stenosis-Remote)/Remote

MBF (ml/min/g)

%Flow reduction (Stenosis-Remote)/Remote

MFR

Stenosis

0.961

35.98

0.714

838.495

0.742

Remote

1.502

8.469

5.638

Experiment 2

Rest

Stress

MBV (ml/100g)

%MBV increase (Stenosis-Remote)/Remote

MBV (ml/100g)

%MBV reduction (Stenosis-Remote)/Remote

MVR

Average

3.241

4.828

1.490

Stenosis

3.669

9.85

4.335

19.94

1.182

Remote

3.340

5.415

1.833

Flow from microspheres

Rest

Stress

MBF (ml/g/min)

%Flow reduction (Stenosis-Remote)/Remote

MBF (ml/g/min)

% Flow reduction (Stenosis-Remote)/Remote

MFR

Stenosis

0.687

25.239

0.908

627.226

1.322

Remote

0.918

6.414

8.583