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Table 1 Genetically confirmed HFE-HC patient group: patient characteristics at time of CMR scan

From: On myocardial siderosis and left ventricular dysfunction in hemochromatosis

Number of patients   31
Male/Female   25/6
Age (years): mean [SD]   58.8 [13.6]
Weight (kg): mean [SD]   80.8 [14.5]
Height (cm): mean [SD]   173 [11.8]
Race Caucasian 31
Genetic mutation analysis: N (%) C282Y/C282Y 30 (97%)
  C282Y/H63D 1 (3%)
Presentation ferritin (μg/L): median [Q1, Q3]; Normal 30-400   1286 [639, 2772]
Iron (μmol/L): mean [SD]; Normal 9-30   43.5 [12.7]
Iron binding saturation (%): mean [SD]; Normal 25-50   67.5 [19.8]
Hb (g/dL): mean [SD]; Normal 13-15   13.6 [1.4]
Liver T2* (ms): median [Q1, Q3]; Normal 26.7 ±4.2 ms   3.0 [1.4, 7.3]
Liver iron concentration (mg/g dw): median [Q1, Q3]   8.7 [3.7, 18.3]
LV EDV/BSA (mL/m2): median [Q1, Q3]; Normal 60-95   77 [64, 88]
LV ESV/BSA (mL/m2): median [Q1, Q3]; Normal 16-36   24 [20, 29]
LV EF (%): median [Q1, Q3]; Normal 58-76   70 [59, 73]
LV mass/BSA (g/m2): median [Q1, Q3]; Normal 53-84   70 [58, 90]
Cardiac T2* (ms): median [Q1, Q3]; Normal 40 ms   34.8 [25.4, 40.1]
Cardiac iron concentration (mg/g dw): median [Q1, Q3]   0.59 [0.50, 0.87]
  1. (BSA body surface area, EDV end-diastolic volume, EF ejection fraction, ESV end-systolic volume, Hb Hemoglobin, LV left ventricle, SD standard deviation, Q1 lower quartile, Q3 upper quartile). Normal values from Westwood [21], and Maceira [22].