Table 3 Unresolved issues in cancer survivors and possible techniques to address these issues
Morbidity | Unresolved question | Proposed MRI technique |
|---|---|---|
Cerebro vascular accident | Accelerated atherosclerosis | Wall thickness of ascending, descending aorta, plaque characterization |
Myocardial infarction | Coronary flow reserve using quantitative myocardial perfusion | |
Peripheral vascular disease | Wall thickness of femoral arteries, BOLD imaging | |
LV systolic dysfunction | Early detection of myocellular injury and risk stratification | T1, T2 and ECV mapping |
Strain imaging | ||
Impairment of myocardial mechanics, i.e. Impaired torsion | Diffusion tensor imaging | |
Myocardial energy metabolism | NMR P32 spectroscopy | |
Impaired exercise tolerance | Arterial stiffness | 4D Flow for assessing pulse wave velocity |
Fatigue | Skeletal muscle injury | NMR spectroscopy to assess for mitochondrial dysfunction in skeletal muscle |
Fat/water separation to assess fat content | ||
Hypertension | Endothelial dysfunction | Flow mediated arterial dilation |