Figure 1

Pulse sequence diagram of PIVOT. A slice-selective (shown by SS only gradient) or non-selective adiabatic inversion pulse labels blood for perfusion imaging. During the PLD a keyhole multi-echo GRE acquires data downstream from the perfusion slice location for SvO₂ (blue) and T₂* (green) analysis. An EPI readout at isocenter (red) is used to acquire the images for perfusion quantification.