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Table 4 Intra-observer, inter-observer and inter-study reproducibility of measurements for all subjects

From: Standardization of T1 measurements with MOLLI in differentiation between health and disease – the ConSept study

Intraobserver 1.5 T   3 T  
Septal SAX Septal SAX
Native T1
MD ± SD (ms) 3 ± 11 -16 ± 23 3 ± 13 -6 ± 16
CoV (%) 1.1 2.3 1.2 1.5
Agreement (r) 0.84** 0.72** 0.87** 0.74**
Post-contrast T1
MD ± SD (ms) 5 ± 12 3 ± 24 -6 ± 15 -3 ± 13
CoV (%) 3.1 6.6 3.2 3.2
Agreement (r) 0.78** 0.53* 0.79** 0.62**
Lambda
MD ± SD 0.014 ± 0.009 -0.017 ± 0.013 0.017 ± 0.002 0.019 ± 0.019
CoV (%) 4.1 5.2 5.1 5.9
Agreement (r) 0.81** 0.69** 0.78** 0.61**
Interobserver 1.5 T   3 T  
  Septal SAX Septal SAX
Native T1
MD ± SD (ms) -1.5 ± 19 2.3 ± 24 0.3 ± 15 -2.9 ± 49
CoV (%) 4.3 6.9 1.4 2.7
Agreement (r) 0.89** 0.73** 0.93** 0.75**
Post-contrast T1
MD ± SD (ms) -6.3 ± 52 -6.9 ± 53 6.2 ± 71 -8.4 ± 79
CoV (%) 4.3 7.1 2.8 3.3
Agreement (r) 0.79** 0.69** 0.81** 0.54**
Lambda
MD ± SD 0.013 ± 0.019 -0.017 ± 0.002 0.019 ± 0.008 0.011 ± 0.003
CoV (%) 7.2 7.9 9.1 11.7
Agreement (r) 0.71** 0.59** 0.68** 0.53**
Interstudy 1.5 T   3 T  
  Septal SAX Septal SAX
Native T1
MD ± SD (msec) 2.4 ± 9.2 6.1 ± 21 -1.5 ± 12 4.9 ± 18
CoV (%) 1.2 4.5 3.6 8.4
Agreement (r) 0.92** 0.78** 0.95** 0.86**
Post-contrast T1
MD ± SD (ms) -8 ± 54 35 ± 72 19 ± 65 31 ± 62
CoV (%) 9.0 12 12 15
Agreement (r) 0.62** 0.45* 0.55** 0.41**
Lambda
MD ± SD 0.017 ± 0.021 0.021 ± 0.029 0.016 ± 0.018 0.019 ± 0.035
CoV (%) 4.2 6.1 3.5 7.8
Agreement (r) 0.79** 0.69** 0.82** 0.73**
  1. Data is expressed as mean ± SD, CoV coefficient of variability, r = Pearson correlation coefficient for agreement between two measurements, p-value < 0.05*, < 0.01** for significant association.