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Table 2 Heart rate and left ventricular cardiac parameters in renal artery stenosis (RAS) or control mice

From: Evolution of cardiac and renal impairment detected by high-field cardiovascular magnetic resonance in mice with renal artery stenosis

 

Baseline

2 weeks

4 weeks

Heart rate (beats per min)

   

RAS

454 ± 17

429 ± 28

426 ± 19#

Control

470 ± 11

472 ± 3

482 ± 23

Left Ventricular Volume (mm3)

   

RAS

   

     End Systole

8.4 ± 1.2

9.1 ± 1.5

8.7 ± 1.4

     End Diastole

33.2 ± 1.4

30.3 ± 2.0#

29.7 ± 1.7#

     Myocardial Volume

53.3 ± 3.7

70.7 ± 3.5*$#

76.6 ± 3.3*$#

  Control

   

     End Systole

9.6 ± 1.3

11.2 ± 0.9

11.8 ± 1.3

     End Diastole

34.3 ± 2.0

35.9 ± 1.2

36.8 ± 2.4

     Myocardial Volume

51.5 ± 0.6

56.6 ± 2.2

61.0 ± 2.2*

Stroke Volume (mm3)

   

  RAS

24.7 ± 1.5

21.1 ± 0.9*$#

20.9 ± 1.3*$#

  Control

24.7 ± 1.0

24.8 ± 1.0

24.9 ± 1.5

Ejection Fraction (%)

   

  RAS

74.7 ± 3.0

71.4 ± 3.2

71.3 ± 3.8

  Control

72.5 ± 2.6

69.1 ± 1.9

71.4 ± 3.2

Cardiac Output (ml/min)

   

  RAS

11.2 ± 0.7

8.5 ± 0.9*$#

8.7 ± 0.7*$#

  Control

11.6 ± 0.4

11.7 ± 0.4

12.7 ± 0.5

E/A Ratio

   

  RAS

1.09 ± 0.08

1.22 ± 0.12

1.40 ± 0.10*$#

  Control

1.09 ± 0.04

1.14 ± 0.03

1.11 ± 0.05

Time to Systole/Diastole

   

  RAS

1.2 ± 0.2

1.3 ± 0.2

1.1 ± 0.1

  Control

1.1 ± 0.1

1.1 ± 0.1

1.1 ± 0.1

  1. *P < 0.05 vs. Baseline RAS, $P < 0.05 vs. Baseline Control, #P < 0.05 vs. Control.
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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