- Poster presentation
- Open Access
Comparison of parameters for left ventricular volumes and function between echocardiography and cardiovascular magnetic resonance in a large group of cardiac patients
© Andre et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Ejection Fraction
- Cardiovascular Magnetic Resonance
- Left Ventricular Volume
- Cardiac Patient
- Cardiovascular Magnetic Resonance Imaging
Left ventricular (LV) volumes and function are of paramount importance for the correct diagnosis finding, cardiovascular risk stratification and assessment of future cardiac events as well as for therapeutic guidance. In clinical routine, echocardiography (EC) is the method of choice due to its wide availability and its straight-forward examination. However, cardiovascular magnetic resonance (CMR) is the gold-standard for the evaluation of cardiac volumes and function. In this study we compared the LV volumes and functional parameters obtained by EC with CMR results in a large group of cardiac patients.
We included 1017 subjects (736 male, 281 female) retrospectively receiving both EC and CMR who presented to our cardiology department. EC was performed on four different systems (Philips IE 33, GE Vivid 7, GE Vivid I, GE Vivid S5) and images were analyzed by experienced readers. LV end-diastolic, end-systolic, and stroke volumes (EDV, ESV, SV) as well as ejection fraction (EF) were measured by two different EC techniques, a) a modified Simpson's rule and b) the Teichholz formula, and compared to the CMR results. CMR imaging was performed on a 1.5 T whole-body MRI using a standard SSFP sequence and short-axis views were obtained for the LV quantification. Analyses of variances were performed between groups and a p<0.05 was regarded as statistically significant. Furthermore a Bland-Altman analysis was conducted plotting against CMR as the gold-standard.
CMR provides higher values than EC for LV volumes and ejections fraction presumably due to its superior blood tissue contrast. Furthermore the values obtained by different EC formulas were significantly different. Interestingly, the discrepancy between CMR and EC was dependent of the absolute LV volume and functional values showing a greater deviation for lower and higher values. As an exact measurement especially in these clinical scenarios is of great therapeutic importance (e.g. indication for an ICD) further studies are needed.
Comparison LV volumetric and functional parameters acquired by CMR and EC (Simpson and Teichholz formula)
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.