- Oral presentation
- Open Access
Right ventricle anatomy can predict new onset ventricular tachycardia in patients with repaired tetralogy of Fallot
© Bonello et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Cardiovascular Magnetic Resonance
- Cardiac Magnetic Resonance
- Ventricular Tachyarrhythmia
- British Heart Foundation
- Biomedical Research Unit
Repaired tetralogy of Fallot (rtoF) patients are at risk ventricular tachyarrhythmia and sudden cardiac death. Risk stratification for arrhythmia remains difficult.
We aimed to investigate whether cardiac anatomy and function assessed by cardiac magnetic resonance imaging (CMR) predict arrhythmia.
One-hundred-and-fifty-four adults with rtoF, median age 30.8 (21.9-40.2) years, were studied with a standardised protocol including cardiovascular magnetic resonance (CMR) and prospectively followed-up over median 5.6 (4.6-7.0) years for the pre-specified endpoints of new-onset ventricular tachyarrhythmia (sustained ventricular tachycardia/ventricular fibrillation).
Conclusions: RVOT akinetic region length predicts ventricular arrhythmia in late follow-up of rtoF. This is simple, feasible measurements for inclusion in serial surveillance and risk stratification of rtoF patients.
British Heart Foundation Fellowship (SVB-N).
French Federation of Cardiology (BB).
Unrestricted Actelion educational grant (GD).
The study was supported by the NIHR Cardiovascular Biomedical Research Unit of Royal Brompton and Harefield NHS Foundation Trust and Imperial College London.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.