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Table 1 Baseline characteristics and cardiac magnetic resonance findings of the study subjects

From: Myocardial steatosis and impaired energetics are independent predictors of regional contractile function in patients with severe aortic stenosis

 

Severe Aortic Stenosis

Normal (n=20)

P value

 

Symptomatic (n=20)

Asymptomatic (n=10)

  

Age (y)

67 ± 11

61 ± 18

62 ± 4

0.14

Male [n (%)]

13 (65)

8 (80)

10 (50)

0.23

Body mass index (kg/m2)

29 ± 4

28 ± 4

26 ± 4

0.09

Aortic valve area (cm2)

0.84 ± 0.15

0.87 ± 0.16

-

0.68

Peak aortic valve gradient (mmHg)

78 ± 17

66 ± 16

-

0.10

Left ventricular ejection fraction (%)

75 ± 6

73 ± 8

69 ± 4

0.10

Left ventricular mass index (g/m2)

98 ± 33*

91 ± 26*

53 ± 13

<0.001

Left ventricular wall thickness (mm)

16 ± 3*

15 ± 2*

9 ± 1

<0.001

Peak systolic circumferential strain (%)

-17.2 ± 2.5*

-18.6 ± 2.8*

-20.1 ± 1.6

0.002

PCr/ATP ratio

1.38 ± 0.17†

1.65 ± 0.26*

1.91 ± 0.29

<0.001

Myocardial lipid content (% of water)

0.85 ± 0.43*

0.74 ± 0.29*

0.44 ± 0.18

0.001

  1. *p<0.05 vs normal, †p<0.05 vs asymptomatic severe aortic stenosis and normal.