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Table 1 Baseline characteristics and cardiac magnetic resonance findings of the study subjects

From: Myocardial steatosis and impaired energetics are independent predictors of regional contractile function in patients with severe aortic stenosis

  Severe Aortic Stenosis Normal (n=20) P value
  Symptomatic (n=20) Asymptomatic (n=10)   
Age (y) 67 ± 11 61 ± 18 62 ± 4 0.14
Male [n (%)] 13 (65) 8 (80) 10 (50) 0.23
Body mass index (kg/m2) 29 ± 4 28 ± 4 26 ± 4 0.09
Aortic valve area (cm2) 0.84 ± 0.15 0.87 ± 0.16 - 0.68
Peak aortic valve gradient (mmHg) 78 ± 17 66 ± 16 - 0.10
Left ventricular ejection fraction (%) 75 ± 6 73 ± 8 69 ± 4 0.10
Left ventricular mass index (g/m2) 98 ± 33* 91 ± 26* 53 ± 13 <0.001
Left ventricular wall thickness (mm) 16 ± 3* 15 ± 2* 9 ± 1 <0.001
Peak systolic circumferential strain (%) -17.2 ± 2.5* -18.6 ± 2.8* -20.1 ± 1.6 0.002
PCr/ATP ratio 1.38 ± 0.17 1.65 ± 0.26* 1.91 ± 0.29 <0.001
Myocardial lipid content (% of water) 0.85 ± 0.43* 0.74 ± 0.29* 0.44 ± 0.18 0.001
  1. *p<0.05 vs normal, p<0.05 vs asymptomatic severe aortic stenosis and normal.