Figure 1

13C dynamic spectra were acquired using a slice selective pulse-and-acquire sequence (bandwidth 5000 Hz, 2048 pts, 10° FA). A long-axis slice of 20 mm was selected during excitation. Spectra were acquired from the beginning of the injection of the hyperpolarized [1-13C] acetate, every 2 s, for 120 s. Diagrammatic representation of the γ-variate and mono-exponential fitting of cardiac spectroscopic signal to obtain rate constants (N=4).