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Table 1 LV parameters for and SCD and TM pediatric patient without cardiac iron overload, with differentiation for gender. All variables are expressed as mean ± SD with 95% confidence intervals in square brackets.

From: Biventricular dimensions and function in pediatric sickle-cell disease and thalassemia major patients without cardiac iron

  SCD TM P P adjusted for systolic BP P adjusted for cardiac R2* P adjusted for both covariates
Males
LV EDVI (ml/m 2 ) 104.7 ± 15.2 [99.5 - 109.9] 88.7 ± 11.0 [84.5 - 92.8] <0.0001 <0.0001 <0.0001 <0.0001
LV ESVI (ml/m 2 ) 38.1 ± 7.4 [35.6 - 40.7] 31.6 ± 5.5 [29.5 - 33.6] <0.0001 <0.0001 0.0003 <0.0001
LV SVI (ml/m 2 ) 66.6 ± 9.5 [63.3 - 69.8] 57.1 ± 6.5 [54.6 - 59.5] <0.0001 <0.0001 <0.0001 <0.0001
LV EF (%) 63.8 ± 3.5 [62.6 - 65.0] 64.7 ± 2.8 [63.6 - 65.7] 0.286    
LV MI (g/m 2 ) 83.5 ± 11.4 [79.1 - 87.9] (27 pts; 45 MRIs) 66.9 ± 7.0 [64.0 - 69.8] (24 pts; 59 MRIs) <0.0001 <0.0001 <0.0001 <0.0001
LV CI (l/min/m2) 4.8 ± 0.6 [4.6 - 5.1] (32 pts; 55 MRIs) 4.5 ± 0.5 [4.4 - 4.7] (29 pts; 74 MRIs) 0.017    
Females
LV EDVI (ml/m 2 ) 93.5 ± 9.6 [90.0 - 97.0] 81.4 ± 6.7 [78.4 - 84.4] <0.0001 <0.0001 <0.0001 <0.0001
LV ESVI (ml/m 2 ) 36.0 ± 5.3 [34.0 - 37.9] 29.4 ± 3.8 [27.6 - 31.1] <0.0001 <0.0001 <0.0001 <0.0001
LV SVI (ml/m 2 ) 57.5 ± 6.3 [55.2 - 59.8] 52.0 ± 4.2 [50.1 - 53.4] 0.0006 0.009   
LV EF (%) 61.6 ± 3.5 [60.4 - 62.9] 64.1 ± 2.9 [62.8 - 65.4] 0.008    
LV MI (g/m 2 ) 72.9 ± 8.9 [69.6 - 79.3] (28 pts; 60 MRIs) 62.8 ± 7.5 [60.4 - 66.1] (18 pts; 40 MRIs) 0.0001 0.0002   
LV CI (l/min/m 2 ) 4.6 ± 0.6 [4.4 - 4.8] (72 MRIs) 4.2 ± 0.5 [3.9 - 4.4] (52 MRIs) 0.006