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Adenosine-perfusion at 1.5 Tesla is superior to 3 Tesla for the detection of coronary artery disease
Journal of Cardiovascular Magnetic Resonance volume 15, Article number: P187 (2013)
To compare a compiled clinical routine cardiac magnetic resonance imaging (CMR) protocol performed at both 1.5-T and 3.0-T in patients with suspected coronary artery disease (CAD) undergoing coronary x-ray angiography.
CMR including adenosine perfusion and late gadolinium enhancement (LGE) at 1.5-T has been established for noninvasive detection of relevant CAD. However, little is known about the potential advantages of 3.0-T to detect CAD.
Fifty-two evaluable patients (62.3 ± 10.2 years) were included into the study. All patients were scanned at both 1.5-T and 3.0-T including adenosine stress and rest perfusion, and LGE imaging. CMR images were analyzed by two blinded readers in consensus. A significant CAD was diagnosed by quantitative coronary analysis.
Diagnostic accuracy of the combined analysis of perfusion and LGE imaging yielded better values at 1.5-T and 3.0-T than the analysis of perfusion images alone. Specificity and sensitivity at 3.0-T was superior to 1.5-T in detecting coronary stenoses ≥50% (90% vs.75% and 84.4% vs.75%) and ≥70% (88% vs. 80% and 96.3% vs. 88.9%).
This study showed that CMR at 3.0-T in a routine clinical setting is superior to 1.5-T in detection of significant CAD. 3.0-T might become the preferred CMR field strength for evaluation of CAD in clinical practice.
This study was partly funded by a research grant of Guerbet, France.
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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Walcher, T., Ikuye, K., Rottbauer, W. et al. Adenosine-perfusion at 1.5 Tesla is superior to 3 Tesla for the detection of coronary artery disease. J Cardiovasc Magn Reson 15 (Suppl 1), P187 (2013). https://doi.org/10.1186/1532-429X-15-S1-P187
- Coronary Artery Disease
- Cardiac Magnetic Resonance
- Late Gadolinium Enhancement
- Cardiac Magnetic Resonance Image
- Significant Coronary Artery Disease