- Poster presentation
- Open Access
High-dose dobutamine stress magnetic resonance perfusion imaging at 3.0 Tesla
© Gebker et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Wall Motion Abnormality
- Steady State Free Precession
- Magnetic Resonance Perfusion Imaging
- Steady State Free Precession Sequence
Dobutamine stress magnetic resonance (DSMR-wall motion) has been established as a valuable tool for the detection of inducible wall motion abnormalities. Additional perfusion imaging during DSMR (DSMR-perfusion) was shown to improve sensitivity for the detection of myocardial ischemia. Current experience is based on 1.5T only, mainly due to insufficient image quality of steady state free precession (SSFP) cine imaging at higher field strengths. Recently, image quality and diagnostic accuracy of SSFP sequences was significantly improved by dual-source parallel radiofrequency (RF) transmission for 3.0T. We examined whether the addition of myocardial perfusion imaging during DSMR at 3.0T is feasible and whether it provides incremental benefit for the evaluation of CAD.
DSMR-wall motion and -perfusion were combined in 48 consecutive patients on 3.0T clinical systems (Philips Achieva and Ingenia, both equipped with a dual-source RF transmission system) applying a standard high dose dobutamine-atropine protocol. Perfusion images were acquired in three short axis views during maximum stress. Wall motion and perfusion images were interpreted sequentially by two blinded readers with invasive coronary angiography serving as the reference standard.
Diagnostic accuracy of DSMR-wall motion and DSMR-perfusion
Coronary stenosis ≥50%
Coronary stenosis ≥70%
DSMR-perfusion is feasible with a high procedural success rate at 3.0T applying dual-source RF transmission and has additional diagnostic value compared to DSMR-wall motion regarding the extent of stress inducible ischemia.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.