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- Open Access
Correlation between congenital bicuspid aortic valve morphology with thoracic aortic dimensions - a retrospective analysis with cardiovascular magnetic resonance
© Tan et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Cardiovascular Magnetic Resonance
- Aortic Arch
- Aortic Root
- Bicuspid Aortic Valve
- Aortic Dilatation
Congenital bicuspid aortic valve (BAV) is the commonest inherited cardiac defect that is often associated with a medley of other cardiovascular anomaly, the most frequent being aortic dilatation which may be a consequent of an interplay between genetic and hemodynamic factors. This retrospective study aims to find a correlation between BAV valve morphology with thoracic aortic dimension with cardiovascular magenetic resonance imaging (CMR).
A retrospective analysis of the aortic valve and aortic (Ao) dimension was made of 149 patients aged between 6 and 77 years (mean age 43±17 ,102 males and 47 females) with BAV who underwent CMR study. BAV patients with associated coarctation or valvular dysfunction were excluded. Images were acquired with either a Siemens Avanto or Sonata 1.5T scanner in orthogonal planes. Aortic maximal intraluminal dimensions in end diastole were measured at the annulus, sinuses, sino-tubular junction, mid ascending aorta, arch and proximal descending aorta. These measurements were indexed according to body surface area (BSA). BAV valve morphology were characterised in cross-sectional steady-state free precession (SSFP) cine images and grouped according to the presence or absence of a raphe.
Median Indexed Aortic Dimension in BAV with raphe and Pure BAV patients
BAV with raphe Median(95%CI) (mm/m2)
Pure BAV Median(95%CI) (mm/m2)
Significance (p value)
Mid Ascending Aorta
Proximal Descending Aorta
Majority of BAV patients have a remnant raphe, commonly between the fused right and left cusps. These patients were also found to have smaller indexed aortic root and ascending aortic dimensions compared with those with ‘pure' BAV which may indicate an inherent difference in biologic aortic structure.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.