Table 2 Univariate and backwards stepwise regression analyses of percentage change in renal medullary tissue oxygenation (T2* signal intensity) in response to a 20 mg intravenous furosemide stimulus
Variables | Univariate | Backwards stepwise regression | ||
|---|---|---|---|---|
Parameter estimate (SE) | p-value | Parameter estimate (SE) | p-value | |
Age | 0.32 (0.29) | 0.28 | ||
Glomerular filtration rate | 0.05 (0.11) | 0.65 | ||
Gender | 2.27 (4.31) | 0.61 | ||
Ethnicity | -14.4 (4.61) | 0.006* | -13.1 (4.09) | 0.004* |
Stenosis severity (%) | -0.12 (0.06) | 0.04* | -0.11 (0.05) | 0.04* |
Diabetes diagnosis | 0.72 (4.61) | 0.88 | ||
Body mass index | -0.49 (0.33) | 0.15 | ||
Chronic daily furosemide dose (mg/day) | -0.09 (0.05) | 0.09 | -0.11 (0.04) | 0.01* |
ACEI/ARB use | 6.41 (4.64) | 0.18 | ||
Antihypertensive medications (number) | 0.98 (1.74) | 0.58 | ||