| Controls N = 20 | SSc N = 19 | P value |
---|---|---|---|
Female sex, n (%) | 19 (95) | 18 (95) | 0.74 |
Age, years | 56 ± 8 | 55 ± 10 | 0.64 |
Hypertension, n (%) | 2 (10) | 4 (21) | 0.41 |
Diabetes, n (%) | 0 | 0 | - |
Hyperlipidaemia, n (%) | 4 (20) | 3 (16) | 0.73 |
BMI, kg/m2 | 25 ± 4 | 27 ± 7 | 0.23 |
SSc VDAI | N/A | 4 ± 2 | - |
ESR, mm/hr (median, IQR) | N/A | 11 (3-18) | - |
CRP, mg/L (median, IQR) | 3 (1-4) | 5 (2-8) | 0.01 |
Hemoglobin (g/L) | 13 ± 1 | 12 ± 1 | 0.05 |
mRSS | N/A | 20 ± 6 | - |
LVEDV indexed, ml/m2 | 77 ± 16 | 69 ± 11 | 0.08 |
LVESV indexed, ml/m2 | 21 ± 5 | 18 ± 5 | 0.06 |
LVEF, % | 73 ± 5 | 74 ± 6 | 0.52 |
LV Mass indexed, g/m2 | 52 ± 11 | 51 ± 8 | 0.74 |
LA size, mm | 28 ± 5 | 37 ± 6 | < 0.001 |
RVEDV indexed, ml/m2 | 85 ± 19 | 77 ± 12 | 0.32 |
RVESV indexed, ml/m2 | 28 ± 7 | 25 ± 7 | 0.06 |
RVEF, % | 67 ± 4 | 67 ± 6 | 0.14 |
Mid SA circumferential strain | -18.6 ± 1.0 | -16.8 ± 1.6 | < 0.001 |
Peak diastolic circumferential strain rate (s-1) | 114 ± 16 | 83 ± 26 | < 0.001 |
Presence of LGE (%) | 0 | 10 (53) | - |
Volume fraction of LGE > 2SD (%) | 0 | 3.8 ± 0.4 | - |
STIR T2 Ratio | 1.6 ± 0.5 | 1.7 ± 0.4 | 0.66 |