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Table 2 Myocardial structure, function and perfusion in SLE patients and controls

From: Abnormal myocardial perfusion correlates with impaired systolic strain and diastolic strain rate in systemic lupus erythematosus: a cardiovascular magnetic resonance study

 

Controls N=29

SLE N=29

P value

LVEDV indexed to BSA, ml/m2

80 ± 15

78 ± 12

0.71

LVESV indexed to BSA, ml/m2

22 ± 6

20 ± 6

0.23

LVEF, %

74 ± 5

72 ± 6

0.54

LV Mass indexed to BSA, g/m2

51 ± 10

48 ± 10

0.18

LA size, mm

26 ± 4

32 ± 5

<0.001

Mid SA circumferential strain

-19.4 ± 1.2

-17.2 ± 1.7

<0.001

Peak diastolic circumferential strain rate (s-1)

118 ± 15

78 ± 24

<0.001

Presence of LGE (%)

0

10 (43)

-

Volume fraction of LGE>2SD (%)

0

2.7 ± 0.3

-

Global myocardial T2 SI Ratio

1.5 ± 0.1

1.7 ± 0.3

0.001

Volume fraction of oedema by T2 (%)

0

17 (7-23)

-

Average myocardial T1, ms

959 ± 28

983 ± 30

0.01

Volume fraction of T1>990ms (%)

3 (1-4)

38 (23-50)

<0.001

ECV (%)

28.1 ± 2.9

30.6 ± 4.0

0.04

Rest RPP

7, 741 ± 1, 308

9, 028 ± 1, 669

0.002

Rest RPP

11, 474 ± 2, 110

13, 140 ± 2, 537

0.009

MPRI

1.9 ± 0.4

1.4 ± 0.2

<0.001

Proportion of non-segmental perfusion defects (%)

0

9 (31)

-

  1. Continuous data are mean ± SD unless otherwise indicated. ECV, extracellular volume; LA, left atrium; LGE, late gadolinium enhancement; LV, left ventricle/ventricular; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end-systolic volume; MPRI, myocardial perfusion reserve index; RPP, rate pressure product; SA, short axis; SI, signal intensity, SLE, systemic lupus erythematosus