- Poster presentation
- Open Access
The prospective study of cardiac MRI in the diagnosis and treatment of cardiac sarcoidosis associated with atrioventricular block
© Kunimoto et al; licensee BioMed Central Ltd. 2015
- Published: 3 February 2015
- Cardiac Magnetic Resonance
- Atrioventricular Block
- Cardiac Sarcoidosis
- Pacemaker Implantation
Between June 2009 and May 2013, one thousand four hundred eighty-seven patients (nine hundred fifty-two males) underwent CMR. We underwent CMR to advanced AVB cases that have been the adaptation of pacemaker implantation of five years if at all possible. CMR was performed by using 1.5-T magnet MR systems (Intera Achieva, Philips Medical Systems) with 5-element cardiac coils. In cases with temporary pacing, CMR scan were performed just behind extraction temporary pacing lead with confirmation of spontaneous beat, which followed by pacemaker implantation. We excluded cases over 85 years old or in severe circulatory failure with AVB.
Sixty-six AVB cases of all fourteen hundred eighty-seven CMR cases underwent CMR for five years. On the other hand, in one hundred fifty-four cases, a pacemaker was newly implanted for AVB and one hundred twenty-five were under 85 years old. Among these cases, CMR scan were performed in fifty (40% of one hundred fifty-five) cases. Thirteen cases (20% of sixty-six) indicate the pattern of CS with late Gd enhancement (LGE). Nine of thirteen cases were diagnosed as CS with criteria and FDG-PET scan. Five cases received steroid therapy and three cases showed improvement of AVB. Especially, pacemaker implantation was able to avoid in one case. Unfortunately one case did not receive steroid therapy at early phase and developed congestive heart failure. In addition, FDG-PET is more useful than Ga scintigram for assessment activity of CS.
CMR in advanced AVB has been accompanied with difficulty because of the bradycardia. Even if only few cases were found as CS in all cases newly pacemaker implanted, its impact on the therapeutic strategy is enormous. In diagnosis of CS, sign of positive LGE and positive PET have important implications. CMR is useful as screening tool for CS and should be performed as far as possible in advanced AVB cases.
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