- Poster presentation
- Open Access
Early detection and quantification of cerebral venous thrombosis by Magnetic Resonance Black Blood Thrombus Imaging (MRBTI)
© Yang et al. 2016
- Published: 27 January 2016
- Imaging Technique
- Venous Thrombosis
- Diagnostic Imaging
- Conventional Imaging
- Imaging Tool
Early diagnosis of cerebral venous and sinus thrombosis (CVT) is currently a major clinical challenge. We proposed a selective MR black-blood thrombus imaging technique(MRBTI).
MRBTI was performed on 23 patients with proven CVT and 24 patients with negative CVT by conventional imaging techniques. Signal-to-noise ratio (SNR) was calculated for the detected thrombus and contrast-to-noise ratio (CNR) was measured between thrombus and lumen, and also between thrombus and brain tissue. The feasibility of using MRBTI for thrombus volume measurement was also explored.
With effectively suppressed blood signal, MRBTI correctly identified 113 out of 116 segments with proven CVT with a sensitivity of 97.4%. In 527 out 531 segments, CVT was ruled out correctly with a specificity of 99.3%. Quantification of thrombus volume was successfully conducted in all patients with CVT, and mean volume of thrombus was 10.5 ± 6.9 cc.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.