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- Open Access
Calculation of differential pulmonary blood flow in patients with congenital heart disease using pulmonary artery flow versus pulmonary vein flow
© Sasaki et al. 2016
- Published: 27 January 2016
- Congenital Heart Disease
- Pulmonary Vein
- Ventricular Outflow Tract
- Flow Ratio
- Branch Pulmonary Artery
Phase contrast magnetic resonance (PCMR) has been shown to provide accurate measurement of differential branch pulmonary artery (BPA) flow in patients with congenital heart disease when compared to the gold standard, lung perfusion scintigraphy (LPS). Although most studies have compared the ratio of net BPA flow volume (NFV) to LPS, one study found that forward flow volume (FFV) correlated more accurately. PCMR quantification of pulmonary venous (PV) flow has also been shown to be feasible and highly reproducible. We sought to calculate differential pulmonary blood flow using PV flow and compare the results with both NFV and FFV calculations.
Retrospective review of 56 patients with congenital heart disease who had phased contrast flow quantification of both branch pulmonary arteries and pulmonary veins during the same study. FFV and NFV of RPA and LPA, as well as their ratios were calculated and were compared to RPV and LPV flow volume.
There were 22 males, and the median age was 12.2 years of age. 37 patients had tetralogy of Fallot and the remainder had other conotruncal abnormalities requiring intervention to the right ventricular outflow tract. Agreement between NFV and PV was superior (intraclass correlation; Ri=0.954 right, Ri=0.857 left, p < 0.001) than FFV and PV (Ri=0.630 right, Ri=0.615 left, p < 0.001). The BPA flow ratio calculated by both NFV and FFV had good agreement with PV flow ratio (Ri=0.904 p < 0.001 and Ri=0.860 p < 0.001, respectively).
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