- Poster presentation
- Open Access
Quantification of the severity of tricuspid regurgitation from cardiac magnetic resonance cine images
© Medvedofsky et al. 2016
- Published: 27 January 2016
- Cardiovascular Magnetic Resonance
- Cardiac Magnetic Resonance
- Tricuspid Regurgitation
- Right Atrium
- Cardiovascular Magnetic Resonance Image
Today, there is no accepted approach to evaluate tricuspid regurgitation (TR) using cardiovascular magnetic resonance (CMR). Contrary to 4-chamber imaging planes, which often do not show the entire regurgitant jet, these jets are readily visualized in short-axis views in the right atrium (RA). We hypothesized that the size and signal intensity (SI) of the cross-sectional jet area in the short-axis views would reflect TR severity.
We studied 61 patients with ≥mild TR on echocardiography, who underwent CMR within 24 hours. The severity of TR was determined by color Doppler vena contracta (VC): severe (VC≥7 mm; N = 20), moderate (3<VC<7 mm; N = 21) and mild (VC≤3 mm; N = 20). CMR TR jet area and mean SI (normalized by that in the RA cavity away from the jet) were measured in a single short-axis frame that depicted maximum area. Receiver-operating characteristic (ROC) analysis was performed on a subgroup of 21 patients for each parameter to determine its diagnostic accuracy for differentiating degrees of TR and the optimal cutoffs, which were then independently tested in the remaining 40 patients.
Measurable regions of signal loss depicting TR jets were noted in 51/61 patients (84%), while 9/10 remaining patients had mild TR by echocardiography. With increasing severity of TR, jet area progressively increased from 6.7 ± 7.5 to 23 ± 14 to 38 ± 20 mm2, while the normalized SI decreased from 74 ± 26 to 39 ± 12 to 22 ± 11% (all p < 0.05). ROC analysis resulted in high AUC values in the derivation group and showed in the test group good accuracy (0.83 for both parameters), which was further improved by combining parameters.
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