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Volume 18 Supplement 1

19th Annual SCMR Scientific Sessions

  • Poster presentation
  • Open Access

Breath-hold imaging of the coronary arteries using quiescent-interval slice-selective (qiss) magnetic resonance angiography - pilot study at 1.5 tesla and 3 tesla

  • 1, 2,
  • 5,
  • 1, 3,
  • 1,
  • 1, 4 and
  • 1, 4
Journal of Cardiovascular Magnetic Resonance201618 (Suppl 1) :P69

https://doi.org/10.1186/1532-429X-18-S1-P69

  • Published:

Keywords

  • Magnetic Resonance Angiography
  • Specific Absorption Rate
  • Coronary Magnetic Resonance Angiography
  • Coronary Magnetic Resonance
  • Respiratory Motion Artifact

Background

Coronary magnetic resonance angiography (MRA) is usually obtained with a free-breathing navigator-gated 3D acquisition. Our aim was to develop an alternative breath-hold approach that would allow the coronary arteries to be evaluated in a much shorter time and without risk of degradation by respiratory motion artifacts. For this purpose, we implemented a breath-hold, non-contrast-enhanced, quiescent-interval slice-selective (QISS) 2D technique. Sequence performance was compared at 1.5 and 3 Tesla using both radial and Cartesian k-space trajectories.

Methods

The left coronary circulation was imaged in six healthy subjects and one patient with coronary artery disease. Breath-hold QISS was compared with T2-prepared 2D balanced steady-state free-precession (bSSFP) and free-breathing, navigator-gated 3D bSSFP.

Results

Approximately 10 2.1-mm thick slices were acquired in a single 20-sec breath-hold using two-shot QISS, and 20 slices using single-shot QISS. QISS contrast-to-noise ratio (CNR) was 1.5-fold higher at 3 Tesla than at 1.5 Tesla. Cartesian QISS provided the best coronary-to-myocardium CNR, whereas radial QISS provided the sharpest coronary images. QISS image quality exceeded that of free-breathing 3D coronary MRA with few artifacts at either field strength. Compared with T2-prepared 2D bSSFP, multi-slice capability was not restricted by the specific absorption rate at 3 Tesla and pericardial fluid signal was better suppressed. In addition to depicting the coronary arteries, QISS could image intra-cardiac structures, pericardium, and the aortic root in arbitrary slice orientations.

Conclusions

Breath-hold QISS is a simple, versatile, and time-efficient method for coronary MRA that provides excellent image quality at both 1.5 and 3 Tesla. Image quality exceeded that of free-breathing, navigator-gated 3D MRA in a much shorter scan time. QISS also allowed rapid multi-slice bright-blood, diastolic phase imaging of the heart, which may have complementary value to multi-phase cine imaging. We conclude that, with further clinical validation, QISS might provide an efficient alternative to commonly used free-breathing coronary MRA techniques.
Figure 1
Figure 1

Examples of thin MIPs reconstructed from single breath hold radial QISS. Images were acquired at 3 Tesla using various scan orientations. A-Aorta and left coronary circulation. B-Right coronary circulation.

Authors’ Affiliations

(1)
Radiology, NorthShore University HealthSystem, Evanston, IL, USA
(2)
Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
(3)
Medicine, Pritzker School of Medicine, University of Chicago, Chicago, IL, USA
(4)
Radiology, Pritzker School of Medicine, University of Chicago, Chicago, IL, USA
(5)
Siemens Healthcare, Chicago, IL, USA

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