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- Open Access
Breath-hold imaging of the coronary arteries using quiescent-interval slice-selective (qiss) magnetic resonance angiography - pilot study at 1.5 tesla and 3 tesla
© Edelman et al. 2016
- Published: 27 January 2016
- Magnetic Resonance Angiography
- Specific Absorption Rate
- Coronary Magnetic Resonance Angiography
- Coronary Magnetic Resonance
- Respiratory Motion Artifact
Coronary magnetic resonance angiography (MRA) is usually obtained with a free-breathing navigator-gated 3D acquisition. Our aim was to develop an alternative breath-hold approach that would allow the coronary arteries to be evaluated in a much shorter time and without risk of degradation by respiratory motion artifacts. For this purpose, we implemented a breath-hold, non-contrast-enhanced, quiescent-interval slice-selective (QISS) 2D technique. Sequence performance was compared at 1.5 and 3 Tesla using both radial and Cartesian k-space trajectories.
The left coronary circulation was imaged in six healthy subjects and one patient with coronary artery disease. Breath-hold QISS was compared with T2-prepared 2D balanced steady-state free-precession (bSSFP) and free-breathing, navigator-gated 3D bSSFP.
Approximately 10 2.1-mm thick slices were acquired in a single 20-sec breath-hold using two-shot QISS, and 20 slices using single-shot QISS. QISS contrast-to-noise ratio (CNR) was 1.5-fold higher at 3 Tesla than at 1.5 Tesla. Cartesian QISS provided the best coronary-to-myocardium CNR, whereas radial QISS provided the sharpest coronary images. QISS image quality exceeded that of free-breathing 3D coronary MRA with few artifacts at either field strength. Compared with T2-prepared 2D bSSFP, multi-slice capability was not restricted by the specific absorption rate at 3 Tesla and pericardial fluid signal was better suppressed. In addition to depicting the coronary arteries, QISS could image intra-cardiac structures, pericardium, and the aortic root in arbitrary slice orientations.
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