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Volume 18 Supplement 1

19th Annual SCMR Scientific Sessions

  • Poster presentation
  • Open Access

Prognostic value of cardiovascular magnetic resonance stress perfusion imaging in patients with atrial fibrillation

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Journal of Cardiovascular Magnetic Resonance201618 (Suppl 1) :P76

  • Published:


  • Atrial Fibrillation
  • Cardiovascular Magnetic Resonance
  • Cardiac Death
  • Perfusion Defect
  • Regadenoson


The purpose of this study was to assess the long-term prognostic value of cardiovascular magnetic resonance (CMR) stress perfusion in patients with atrial fibrillation who had suspected and known coronary artery disease (CAD) at initial stress CMR.


130 consecutive patients with atrial fibrillation referred for perfusion stress CMR using either adenosine or regadenoson were followed for hard cardiovascular events defined as cardiac death or non-fatal myocardial infarction (MACE). Ischemia was defined as new onset of perfusion defects in at least two myocardial segments (positive test). Multivariable Cox regressions for MACE were performed to determine the prognostic value of CMR stress perfusion.


Hard cardiac events occurred in 4 (3.1%) patients during the follow-up period (mean: 21 ± 17 months). Patients without inducible perfusion defects (ischemia) experienced a substantially lower cumulative hard cardiovascular event rate (1%) than in patients with ischemia (9.1%) (p = 0.035) after 5 years (see Kaplan-Meier-curve).


CMR stress perfusion in patients with atrial fibrillation can accurately identify patients, who are at increased risk for cardiac death and myocardial infarction, separating them from those with normal findings, who have a very low risk for future cardiac events.
Figure 1
Figure 1

Kaplan-Meier-curve demonstrating the prognostic value of stress perfusion CMR in 130 patients with atrial fibrillation. Patients have been stratified dependent on the onset of inducible ischemia (perfusion defects).

Authors’ Affiliations

Cardiology, German Heart Institute Berlin, Berlin, Germany
Tbilisi Heart and Vascular Clinic, Tbilisi, Georgia
Dar Al Fouad Hospital, Cairo, Egypt
Philips Healthcare, Hamburg, Germany


© Bigvava et al. 2016

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.