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- Open Access
Prognostic value of cardiovascular magnetic resonance stress perfusion imaging in patients with atrial fibrillation
© Bigvava et al. 2016
- Published: 27 January 2016
- Atrial Fibrillation
- Cardiovascular Magnetic Resonance
- Cardiac Death
- Perfusion Defect
The purpose of this study was to assess the long-term prognostic value of cardiovascular magnetic resonance (CMR) stress perfusion in patients with atrial fibrillation who had suspected and known coronary artery disease (CAD) at initial stress CMR.
130 consecutive patients with atrial fibrillation referred for perfusion stress CMR using either adenosine or regadenoson were followed for hard cardiovascular events defined as cardiac death or non-fatal myocardial infarction (MACE). Ischemia was defined as new onset of perfusion defects in at least two myocardial segments (positive test). Multivariable Cox regressions for MACE were performed to determine the prognostic value of CMR stress perfusion.
Hard cardiac events occurred in 4 (3.1%) patients during the follow-up period (mean: 21 ± 17 months). Patients without inducible perfusion defects (ischemia) experienced a substantially lower cumulative hard cardiovascular event rate (1%) than in patients with ischemia (9.1%) (p = 0.035) after 5 years (see Kaplan-Meier-curve).
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