Figure 2

Representative images (A) of least diffusion weighted (b0), diffusion weighted (DW), MD, FA, and LGE of a baseline measurement 4 weeks after MI. Scar is demarcated with increases in MD, decreases in FA, and increase in LGE signal. Representative helix angle vs transmural depth plots (B) before (red line) and after (black dotted line) treatment. Note the placebo treatment causes the slope of the line to flatten out (slope à 0) indicating less helical transmurality, while exosome treatment maintains the helical transmurality.